Status:

RECRUITING

Study of Cabozantinib in Participants With Neuroendocrine Tumors Who Have Already Received Prior Treatment

Lead Sponsor:

Ipsen

Conditions:

Neuroendocrine Tumors

Eligibility:

All Genders

18+ years

Brief Summary

This study will assess how well cabozantinib works and how safe it is in adults with a type of cancer called neuroendocrine tumors (NETs). These tumors can appear in all parts of the body. All partic...

Eligibility Criteria

Inclusion

  • Participants can join the study if they meet all of the following conditions:
  • Are 18 years or older and able to give informed consent.
  • Have a physician-initiated decision to start treatment with cabozantinib for neuroendocrine tumors (NETs), made before joining the study.
  • Have unresectable or metastatic, well-differentiated pancreatic (pNET) or extra-pancreatic neuroendocrine tumors (epNET).
  • Have already received at least one prior systemic therapy, other than somatostatin analogues.
  • Have signed a written informed consent form.

Exclusion

  • Participants cannot join the study if:
  • They are currently participating in an interventional clinical trial, or have done so within the last 3 months before joining this study.
  • They have a contraindication to cabozantinib treatment, based on the product's official prescribing information.

Key Trial Info

Start Date :

December 17 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2028

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT07314164

Start Date

December 17 2025

End Date

December 31 2028

Last Update

February 27 2026

Active Locations (18)

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Page 1 of 5 (18 locations)

1

Medizinische Universitaet Graz

Graz, Austria

2

MVZ am Klinikum Aschaffenburg

Aschaffenburg, Germany

3

Evangelische Lungenklinik Berlin

Berlin, Germany

4

Krankenhaus St. Joseph-Stift Bremen GmbH

Bremen, Germany