Status:
RECRUITING
Amputations in Childhood and Neuropathic Pain
Lead Sponsor:
Hopitaux de Saint-Maurice
Conditions:
Pediatric
Neuropathic Pain
Eligibility:
All Genders
5-18 years
Brief Summary
This observational study aims to assess the presence of neuropathic pain in children and adolescents who underwent limb amputation during childhood. The study focuses on two types of neuropathic pain...
Detailed Description
Pediatric limb amputations are rare and may occur in the context of trauma, infection, tumors, or congenital malformations. In some congenital conditions, such as proximal femoral focal deficiency, th...
Eligibility Criteria
Inclusion Criteria:
- Patients aged between 5 and 18 years (inclusive) (Piaget's concrete operational stage to be able to complete the self-assessment questionnaires)
- Patients who underwent amputation before the age of 15 for girls and 16 for boys (average age of completion of lower limb growth)
- Patients who have not undergone surgery on the amputated limb for at least one year (to avoid bias, as any surgery involving incision can cause temporary neuropathic pain unrelated to the amputation)
- Have obtained the signature of the non-objection form by both parents/legal guardians
- Have obtained the child's consent (verbal consent but recorded)
- Be affiliated with a health insurance plan.
Exclusion Criteria:
- Patients who do not speak French
- Patients whose cognitive abilities are insufficient (as determined by a clinician or reported by parents) to be able to complete self-assessment questionnaires
- Patients undergoing chemotherapy (due to transient neuropathic pain)
- Patients who have received chemotherapy and whose side effects have not yet subsided (on a case-by-case basis depending on the chemotherapy used)
- Patients who have received chemotherapy causing neuropathic pain due to this treatment that has not disappeared.
- Patients placed under protective custody.
Key Trial Info
Start Date :
February 19 2026
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 2 2027
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT07401966
Start Date
February 19 2026
End Date
February 2 2027
Last Update
February 23 2026
Active Locations (1)
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1
Hôpitaux Paris Est Val-de-Marne - Centre de Référence des Malformations des Membres
Saint-Maurice, France, 94410