Status:
RECRUITING
Influence of Physical Exercise on Neuroplasticity and Sensorimotor Networks in Older Adults
Lead Sponsor:
Universite du Littoral Cote d'Opale
Conditions:
tDCS
Physical Activity + tDCS
Eligibility:
All Genders
20-80 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate the influence of a single session of moderate aerobic exercise on motor cortex neuroplasticity in older adults, both alone and in combination with transcran...
Detailed Description
Aging is associated with structural and functional changes in the central nervous system that may negatively impact motor control, postural stability, upper-limb coordination, and adaptive motor behav...
Eligibility Criteria
Inclusion
- Men or women aged 20 to 35 for the younger group and 65 to 80 for the older group.
- Healthy right-handed or left-handed subjects.
- Subjects who have signed an informed consent form.
- Ability to understand spoken and written French to follow study procedures.
- Subjects affiliated with or beneficiaries of a social security system.
Exclusion
- History of psychaitric disorders : individuals with mental retardation or severe impairment of cognitive, behavioral, or emotional functions that prevent them from understanding the protocol and signing the informed consent form.
- Neurological history (epilepsy, stroke, brain or spinal cord surgery, and history of neurological diseases affecting motor skills and sensitivity, such as multiple sclerosis, neurodegenerative diseases such as Parkinson's or Alzheimer's).
- Inability to give informed consent (e.g., dementia, significant hearing impairment, insufficient language proficiency).
- Contraindications to TMS and tDCS : uncontrolled epilepsy, intracranial metallic foreign body, hearing aid or cochlear implant, implanted stimulator or pump, scalp skin lesion, high intracranial pressure, cerebrospinal fluid shunt).
- Presence of a cardiac pacemaker or other implanted electronic medical device.
- Use of psychotropic drugs.
- Individuals under legal guardianship or curatorship.
- Pregnant and breastfeeding women.
- Inability or recognized contraindication to physical activity.
Key Trial Info
Start Date :
February 4 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT07438808
Start Date
February 4 2026
End Date
July 1 2026
Last Update
February 27 2026
Active Locations (1)
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1
Eurasport
Loos, Nord, France, 59120