Status:

RECRUITING

Danicopan PMS in Korea

Lead Sponsor:

AstraZeneca

Conditions:

Paroxysmal Nocturnal Hemoglobinuria

Eligibility:

All Genders

Brief Summary

As part of a post-approval commitment, the Korean health authority requests a study to characterize safety and effectiveness in patients who are treated with Danicopan as an add-on to ravulizumab or e...

Detailed Description

The objectives of this study are to assess the safety and effectiveness of Danicopan in a real world setting in patients who are prescribed with the study drug under the approved indication in Korea. ...

Eligibility Criteria

Inclusion Criteria:

  1. Patients eligible for and treated with Danicpan as add-on therapy to a C5 inhibitor (Eculizumab or Ravulizumab) in patient with PNH in Korea
  2. Provision of a signed and dated written informed consent by the patient or their legally acceptable representative

Exclusion Criteria:

  1. Participation in any concurrent interventional trials during the period of study drug treatment
  2. Other off-label indications according to the approved label in Korea

Key Trial Info

Start Date :

April 10 2026

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 27 2028

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT07457151

Start Date

April 10 2026

End Date

June 27 2028

Last Update

April 17 2026

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Research Site

Busan, South Korea

2

Research Site

Daegu, South Korea

3

Research Site

Hwasun-gun, South Korea

4

Research Site

Seoul, South Korea

Danicopan PMS in Korea | DecenTrialz