Status:

RECRUITING

A Multi-omic Approach to the Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease (CMT1A)

Lead Sponsor:

University Medical Center Goettingen

Collaborating Sponsors:

Assistance Publique Hopitaux De Marseille

Conditions:

CMT

CMT (Charcot Marie Tooth Disease)

Eligibility:

All Genders

10-30 years

Brief Summary

The most common inherited neuropathy is Charcot-Marie-Tooth disease type 1A (CMT1A), caused by a duplication of the gene expressing PMP22. CMT1A patients develop symptoms in early childhood with varia...

Eligibility Criteria

Inclusion criteria:

  • collaborative children, adolescents and young adults aged 10-30 years
  • genetic diagnosis of CMT1A, or clinical diagnosis and genetic diagnosis in affected relatives
  • able to walk with/ without support.

Exclusion Criteria:

  • neuromuscular disorders other than CMT1A
  • concomitant disease preventing correct patient evaluation and contraindication to qMRI

Key Trial Info

Start Date :

March 24 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2026

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT07476365

Start Date

March 24 2025

End Date

September 30 2026

Last Update

April 13 2026

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University Medical Centre

Göttingen, Germany, 37075

A Multi-omic Approach to the Identification of Novel Biomarkers in Early Charcot-Marie-Tooth 1A Disease (CMT1A) | DecenTrialz