Actively Recruiting
Abbott Cephea Mitral Valve Disease Registry
Led by Abbott Medical Devices · Updated on 2026-05-12
1000
Participants Needed
22
Research Sites
172 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of this registry is to gather clinical data on symptomatic patients with mitral valve disease, including patients with mitral regurgitation, mitral stenosis, and mixed mitral valve disease. Data collected from this registry are expected to improve our understanding of the impact of correcting symptomatic mitral valve disease on clinical outcomes in patients that could be candidates for Transcatheter Mitral Valve Replacement and may also inform future regulatory or reimbursement submission strategies for the Cephea Mitral Valve System.
CONDITIONS
Official Title
Abbott Cephea Mitral Valve Disease Registry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Symptomatic mitral valve disease causing mitral regurgitation and/or severe mitral valve stenosis
- New York Heart Association (NYHA) Functional Class II, III, or ambulatory IV
- Transcatheter therapy deemed more appropriate than conventional surgery by the Site Heart Team
- Patient has been adequately treated for coronary artery disease, left ventricular dysfunction, and heart failure
- Age 18 years or older at time of consent
- Patient agrees to study requirements and provides written informed consent
You will not qualify if you...
- Prior surgical or interventional treatment that interferes with Cephea valve delivery or function
- Undergoing dialysis or has chronic renal failure
- Chronic lung disease requiring continuous home oxygen or chronic oral steroid use
- Comorbidities likely to limit life expectancy to less than 12 months
- Pregnant, nursing, or planning pregnancy during follow-up period
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 22 locations
1
Phoenix Cardiovascular Research Group
Phoenix, Arizona, United States, 85016
Actively Recruiting
2
Los Robles Regional Medical Center
Thousand Oaks, California, United States, 91360
Actively Recruiting
3
Piedmont Heart Institute
Atlanta, Georgia, United States, 30309
Actively Recruiting
4
Emory University Hospital
Atlanta, Georgia, United States, 30322
Actively Recruiting
5
Northwestern Memorial Hospital
Chicago, Illinois, United States, 60611
Actively Recruiting
6
Ascension St. Vincent
Indianapolis, Indiana, United States, 46240
Actively Recruiting
7
Via Christi Regional Medical Center - St. Francis Campus
Wichita, Kansas, United States, 67214
Actively Recruiting
8
Minneapolis Heart Institute
Minneapolis, Minnesota, United States, 55407
Actively Recruiting
9
Providence St. Patrick Hospital
Missoula, Montana, United States, 59802
Actively Recruiting
10
St. Francis Hospital
Roslyn, New York, United States, 11576
Actively Recruiting
11
Montefiore Medical Center - Moses Campus
The Bronx, New York, United States, 10467
Actively Recruiting
12
Atrium Health - Carolinas Medical Center
Charlotte, North Carolina, United States, 28203
Actively Recruiting
13
The Cleveland Clinic Foundation
Cleveland, Ohio, United States, 44195
Actively Recruiting
14
Allegheny General Hospital - ASRI
Pittsburgh, Pennsylvania, United States, 15212
Actively Recruiting
15
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
16
TriStar Centennial Medical Center
Nashville, Tennessee, United States, 37203
Actively Recruiting
17
Ascension Saint Thomas
Nashville, Tennessee, United States, 37205
Actively Recruiting
18
Vanderbilt Heart & Vascular Institute
Nashville, Tennessee, United States, 37232
Actively Recruiting
19
Houston Methodist
Houston, Texas, United States, 77030
Actively Recruiting
20
UTHealth Memorial Hermann
Houston, Texas, United States, 77030
Actively Recruiting
21
Intermountain Medical Center
Murray, Utah, United States, 84107
Actively Recruiting
22
Sentara Norfolk General Hospital
Norfolk, Virginia, United States, 23507
Actively Recruiting
Research Team
C
Cephea Project Manager
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here