Risk Factors and Outcomes of Laparoscopic Surgery in Children and Adolescents with Abdominal Neuroblastoma and Related Tumors

What this Trial Is About

Researchers are evaluating the role and impact of various surgical risk factors in laparoscopic surgery for abdominal neuroblastoma, including benign ganglioneuroma and high-risk neuroblastoma. The study aims to develop a new risk scoring system to better understand which factors influence surgical outcomes, such as tumor size, image-defined risk factors IDRF, tumor location, and previous treatments. This observational phase III study builds on existing experience with minimally invasive surgery in this condition. Eligible patients undergo laparoscopic neuroblastoma resection after surgical risk factors are assessed. During surgery, researchers monitor factors like operation duration, blood loss, complications, and if conversion to open surgery is needed. Post-surgery, patients have contrast-enhanced abdominal CT scans for five days to check completeness of tumor removal, with follow-up assessments for complications over 30 days and local recurrence-free survival evaluated at 1, 3, and 5 years. Participants are involved in preoperative imaging and surgical treatment, followed by detailed postoperative monitoring including imaging and complication tracking. Researchers assess surgical duration, risk factors influence, conversion rates to open surgery, surgeons tumor resection assessment, and long-term local recurrence. The total follow-up period extends up to five years to monitor outcomes and tumor recurrence.

Abdominal Neuroblastoma Laparoscopic Surgery Risk Factors Stratification