What is this study trying to find out about proximal femur replacement?

This study is evaluating how different methods of reattaching the abductor muscles during proximal femur replacement affect patient function. Researchers want to learn which technique leads to better recovery and develop a simple way to check muscle function using X-rays. The study is sponsored by Duke University and focuses on improving outcomes after surgery for bone cancers and metastases.

Who may be eligible for this proximal femur replacement clinical trial?

People aged 16 to 75 who have had or are scheduled for proximal femur replacement surgery by an orthopedic oncology surgeon may be eligible. Participants must be able to walk before and after surgery and able to attend follow-up visits. The study accepts all genders. Please review eligibility criteria for more details.

Is there any cost to participate in this proximal femur replacement clinical trial?

Study-related care, including procedures and all trial visits, is provided at no cost. However, personal travel expenses to attend appointments may vary and are not always covered. Participants can expect to receive evaluations and monitoring throughout the study without charge.

Actively Recruiting

Age: 16Years - 75Years

All Genders

ID03261544

Abductor Reattachment Methods in Proximal Femur Replacements: What is the Best Method?

Led by Duke University · Updated on 2025-08-22

Participants Needed

Research Sites

74 weeks

Total Duration

AI-Summary

What this Trial Is About

This research aims to evaluate how different methods of reattaching the abductor muscles during proximal femur resection and reconstruction with an endoprosthesis affect patient function. The study focuses on patients treated at Duke University Medical Center by orthopedic oncology surgeons for conditions such as sarcoma and bone metastases. Researchers want to find out if directly attaching the abductors to the prosthesis leads to better functional outcomes and develop a simple way to assess this function using routine X-rays during follow-up visits. The study involves reviewing up to 300 patient records retrospectively to identify those who had a proximal femur replacement. From these, 50 patients will be consented: 25 who have upcoming clinic visits and 25 who are scheduled for surgery. The intervention under observation is the proximal femur replacement procedure with different abductor muscle repair techniques. There is no drug or placebo; instead, the focus is on surgical methods and outcomes after the procedure. Participants will be followed for up to 24 months after surgery to assess their recovery and function. This includes measuring function with the Musculoskeletal Tumor Society score and Harris Hip Score, tracking any implant-related complications, and performing gait analysis. Clinical visits will include plain radiographs to evaluate abductor muscle function. The study also monitors safety and adverse events during this period, providing a comprehensive view of patient outcomes after their proximal femur replacement.