Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT06438692

Ablation Strategies for Persistent Atrial Fibrillation Combined With Heart Failure

Led by Qianfoshan Hospital · Updated on 2024-06-03

130

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

(1) To evaluate the efficacy and safety of "2C3L" strategy combined with VOM anhydrous ethanol chemical ablation for persistent atrial fibrillation complicated with heart failure; (2) To evaluate the effectiveness of high-efficiency ablation of atrial fibrillation complicated with heart failure.

CONDITIONS

Official Title

Ablation Strategies for Persistent Atrial Fibrillation Combined With Heart Failure

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 80 years
  • First ablation procedure for non-valvular atrial fibrillation
  • Persistent atrial fibrillation with left ventricular ejection fraction (LVEF) 40% or less
  • Symptoms related to atrial fibrillation such as palpitations, syncope, fatigue, or shortness of breath with NYHA class II to IV heart function
  • No response or intolerance to antiarrhythmic drugs, or unwillingness to take them
Not Eligible

You will not qualify if you...

  • Paroxysmal atrial fibrillation
  • Atrial fibrillation caused by clear reversible conditions
  • Left atrial diameter of 60 mm or more by echocardiography
  • Left ventricular ejection fraction greater than 40%
  • Receiving dual antithrombotic therapy
  • Contraindications to oral anticoagulants
  • Contraindications to right or left heart catheterization
  • Pregnancy
  • Life expectancy less than 1 year due to conditions like advanced cancer or kidney disease
  • Unable to stop antiarrhythmic drugs for reasons other than atrial fibrillation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Hesheng Hu

Jinan, Shandong, China, 250012

Actively Recruiting

Loading map...

Research Team

H

Hesheng Hu

CONTACT

X

Xinran Li

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here