Actively Recruiting
Absorbable Versus Non-absorbable Sutures for Wound Closure in Carpal Tunnel Release: a Randomized Controlled Trial
Led by Gelre Hospitals · Updated on 2025-08-26
2604
Participants Needed
2
Research Sites
4 weeks
Total Duration
On this page
Sponsors
G
Gelre Hospitals
Lead Sponsor
D
Deventer Ziekenhuis
Collaborating Sponsor
AI-Summary
What this Trial Is About
Carpal Tunnel Syndrome is a common condition that causes symptoms like tingling, pain, numbness, and weakness. Surgery called carpal tunnel release is the most effective treatment. This research compares two types of sutures used to close wounds after surgery — absorbable and non-absorbable — to see if one type affects the chance of wound infection. The study is a randomized controlled trial investigating how sutures influence infections after surgery. Participants will receive carpal tunnel release surgery where the flexor retinaculum is cut to relieve pressure. After surgery, wounds will be closed using either absorbable sutures (Vicryl rapide or Safil quick) or non-absorbable sutures (Ethilon or Flexocrin). Both suture types are commonly used, but this study aims to find if one leads to fewer infections. The trial does not use masking, and participants are randomly assigned to one of the two suture groups. During the study, researchers will assess wound healing using the ASEPSIS wound score between 10 and 14 days after surgery. Patients will also record their pain using a Numeric Rating Scale for up to three weeks after surgery. Use of antibiotics, hand therapy, and any extra doctor visits will be recorded. The study is sponsored by Gelre Hospitals and includes adult participants aged 18 and older. Participation may last several weeks for follow-up and assessments.
CONDITIONS
Brief Title
abSorbable vErsus Non-absorbable SuturEs for Wound Closure in Carpal Tunnel Release
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Indication for carpal tunnel release surgery
- Adults aged 18 years or older
You will not qualify if you...
- Previous surgery for carpal tunnel syndrome
- Injection with corticosteroids for carpal tunnel syndrome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 10 to 14 days
Participants undergo carpal tunnel release surgery with either absorbable or non-absorbable sutures for wound closure.
1 surgery visit and approximately 1 post-operative visit
Duration - Up to 3 weeks post surgery
Participants record their pain scores and are monitored for wound healing and infection.
Weekly visits or assessments during the first 3 weeks
Trial Site Locations
Total: 2 locations
1
Gelre Ziekenhuizen
Apeldoorn, Netherlands, 7334DZ
Actively Recruiting
2
Deventer Ziekenhuis
Deventer, Netherlands, 7416SE
Actively Recruiting
Research Team
P
Pauline Verhaegen, MD PHD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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