Actively Recruiting

Phase Not Applicable
Age: 40Years - 65Years
All Genders
Healthy Volunteers
NCT06919328

Absorption and Tolerability of Injectable Administration of Niagen®+, as Compared to NAD+

Led by Nutraceuticals Research Institute · Updated on 2025-04-09

70

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

Sponsors

N

Nutraceuticals Research Institute

Lead Sponsor

C

ChromaDex, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study evaluates the subjective effects of injection administration of NR on healthy adult populations.

CONDITIONS

Official Title

Absorption and Tolerability of Injectable Administration of Niagen®+, as Compared to NAD+

Who Can Participate

Age: 40Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed and dated informed consent form
  • Willingness and ability to comply with all study procedures and availability for the study duration
  • Lives within 100 miles of the NRI study site
  • Any gender, aged 40 to 65 years inclusive
  • Good general health based on medical history
  • Body mass index (BMI) between 25 and 34.9 kg/m2
  • Sedentary behavior defined as less than 20 minutes per day or 100 minutes per week of moderate to vigorous exercise
  • Demonstrated fatigue with a below-average score on the Fatigue Assessment Scale
  • For females of reproductive potential: use of highly effective contraception for at least 1 month prior to screening and agreement to use it during the study and for 1 month after
  • Agreement to follow lifestyle considerations during the study
Not Eligible

You will not qualify if you...

  • Current diagnosis of seizure disorder, diabetes or insulin resistance, kidney or liver disorder, heart disease, anemia, cancer, or Parkinson's disease
  • Any chronic illness (pre-disease state allowed)
  • Out of range phosphate levels at baseline
  • BMI less than 25 or greater than or equal to 35
  • Pregnancy, trying to conceive, or breastfeeding
  • Known allergic reactions to any intervention components, including any form of vitamin B3
  • Positive COVID-19 test within 30 days of the study
  • Recent significant weight changes (10% body weight change in last 6 months)
  • Use of NAD+ or NAD precursor supplements, including B-complex, within 60 days before the study, excluding multivitamins
  • Starting new medications, supplements, investigational drugs, or lifestyle changes within 60 days before the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Nutraceuticals Research Institute

Huntsville, Alabama, United States, 35801

Actively Recruiting

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Research Team

J

JESSIE HAWKINS, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

9

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Absorption and Tolerability of Injectable Administration of Niagen®+, as Compared to NAD+ | DecenTrialz