Actively Recruiting
Accelerated iTBS for Post Partum Depression
Led by Medical University of South Carolina · Updated on 2025-09-11
40
Participants Needed
1
Research Sites
500 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Study 1: The investigators are studying the feasibility and tolerability of 10x/day intermittent theta burst (excitatory) transcranial magnetic stimulation to the left dorsolateral prefrontal cortex over the course of 6 days for women with post-partum depression. The investigators further aim to characterize the anticipated anti-depressant effect of this treatment paradigm. Study 2: The investigators are studying the feasibility and tolerability of 12 sessions/day of intermittent theta burse (excitatory) transcranial magnetic stimulation to the left dorsolateral prefrontal cortex over 5 days for women with post-partum depression. The investigators aim to compare the two different treatment schedules.
CONDITIONS
Official Title
Accelerated iTBS for Post Partum Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to provide informed consent and complete assessment tools
- Female, 18 years or older
- Diagnosed with post-partum depression with symptom onset within the first year after childbirth
- Baseline Hamilton Rating Scale for Depression 17-item (HRSD17) score of 14 or higher
You will not qualify if you...
- Currently pregnant
- Moderate or severe substance use disorder (except tobacco use disorder)
- Current psychotic symptoms
- History of dementia or cognitive impairment
- Active suicidal thoughts requiring hospitalization or suicide attempt within past 3 months
- Contraindications to rTMS such as metal implants above the neck, history of seizures, or known brain lesions
- Unstable general medical conditions
- History of eclampsia during pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
Research Team
L
Lisa McTeague, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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