Actively Recruiting
Accelerated Rehabilitation in Individuals After Total Knee Arthroplasty
Led by Mahidol University · Updated on 2026-01-06
32
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary aim of this double-blind randomized controlled trial is to evaluate the effectiveness of an accelerated rehabilitation protocol on knee joint function and quality of life in individuals undergoing TKA compared to conventional rehabilitation in Dali, Yunan, China. The study will include patients aged 50-80 years who are scheduled for primary unilateral TKA. Participants will be randomly assigned to either an accelerated rehabilitation group or conventional rehabilitation group. The primary outcomes will include knee joint function, assessed using the KOOS and quality of life measures using the SF-36 surveys. The study will follow participants for 6 months post-surgery to assess longer-term outcomes. This study will not include individuals undergoing revision TKA or those with severe comorbid conditions. The results will provide critical insights into the role of accelerated rehabilitation in improving post-operative recovery, functional outcomes, and overall quality of life for TKA patients.
CONDITIONS
Official Title
Accelerated Rehabilitation in Individuals After Total Knee Arthroplasty
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with end-stage knee OA necessitating primary unilateral TKA.
- Aged between 50 and 80 years.
You will not qualify if you...
- History of joint infections, cancer, or inflammatory arthritis.
- End-stage OA from rheumatoid or septic arthritis.
- Neurological disorders such as Alzheimer's disease, Parkinson's disease, or stroke.
- Unable to follow a structured rehabilitation protocol.
- Previous knee surgeries other than arthroscopy.
- Severe comorbidities hindering participation, such as advanced cardiovascular diseases.
- Severe osteoporosis.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Hospital
Dali, Yunnan, China
Actively Recruiting
Research Team
L
Liying Yang, PT, M.Sc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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