Actively Recruiting

Phase Not Applicable
Age: 60Years +
All Genders
Healthy Volunteers
NCT05624879

Accelerated Resolution Therapy for Early Maladaptive Grief

Led by Mayo Clinic · Updated on 2025-09-25

440

Participants Needed

4

Research Sites

225 weeks

Total Duration

On this page

Sponsors

M

Mayo Clinic

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose study is to test the effects of accelerated resolution therapy (ART) on pre-loss grief and prolonged grief disorder among older adult family caregivers (FCGs). Additionally, to better understand predictors of response to ART, and cognitive processes that occur among grieving individuals following ART.

CONDITIONS

Official Title

Accelerated Resolution Therapy for Early Maladaptive Grief

Who Can Participate

Age: 60Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Primary caregiver of immediate family member who has a life expectancy of less than 12 months
  • Score of 30 or higher on the PG-12-R, indicating clinically significant pre-loss grief
  • Denial of suicidal ideation or intent, with no evidence of psychotic behavior.
Not Eligible

You will not qualify if you...

  • Since becoming a family caregiver, engaged in another trauma based psychotherapeutic regimen (EMDR, prolonged exposure therapy, trauma focused cognitive behavioral therapy) that could influence response to ART
  • Self-reported or clinically assessed major psychiatric disorder (e.g., bipolar disorder, schizophrenia)
  • Score of > 2 on the adapted CAGE questionnaire indicating alcohol or drug dependence
  • Cognitive impairment (SPMSQ > 4 errors)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Mayo Clinic Arizona

Phoenix, Arizona, United States, 85054

Actively Recruiting

2

Suncoast Hospice

Clearwater, Florida, United States, 33760

Actively Recruiting

3

Mayo Clinic Florida

Jacksonville, Florida, United States, 32224

Actively Recruiting

4

Mayo Clinic

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

K

Katharine E Sheffield, MA, CCRP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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