Actively Recruiting

Phase Not Applicable
Age: 25Years - 49Years
FEMALE
Healthy Volunteers
ID07050745

Accelerating Adoption of Patient-centered Cervical Cancer Screening and Treatment Linkage in Kenya

Led by Kenyatta National Hospital · Updated on 2026-01-12

1980

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

K

Kenyatta National Hospital

Lead Sponsor

E

Emory University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to evaluate a multi-component care strategy called DADA LINK to improve cervical cancer screening and treatment connection among women aged 25 to 49 years in Kenya. The highest rates of cervical cancer occur in sub-Saharan Africa, with it being the leading cause of cancer death among Kenyan women. This study focuses on overcoming barriers at the patient, provider, and facility levels by using tailored strategies based on earlier research and clinic assessments in Nairobi County. The trial compares clinics using the DADA LINK integrated care package, which includes HPV self-sampling kits, care navigation by trained non-physician staff, and use of a mobile health platform called WEMA, against clinics continuing usual care practices. Care coordinators at intervention clinics motivate staff to follow cervical cancer care guidelines, collect patient exit survey data, and manage screening and treatment tracking through the WEMA app. The study lasts 12 months, with an additional 6-month follow-up to assess costs and maintenance of the care strategies. Participants' cervical cancer screening and treatment data will be collected from clinic records by study staff. Researchers will measure how many women complete screening during clinic visits and how many receive follow-up triage or treatment within 12 months. The WEMA system also supports communication with patients via text messages to improve attendance. This comprehensive monitoring aims to assess both the implementation and effectiveness of the care package over the study period.

CONDITIONS

Brief Title

Accelerating Adoption of Patient-centered Cervical Cancer Screening and Treatment Linkage in Kenya

Who Can Participate

Age: 25Years - 49Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Women ages 25 to 49 years
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Women 6 weeks postpartum or less
  • Women already confirmed to have cervical cancer

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - Up to 12 months

Participants receive HPV self-sampling kits and support from care navigators using an mHealth platform to facilitate cervical cancer screening and linkage to treatment.

Visits as needed for screening and follow-up

Follow-up

Duration - Up to 12 months

Participants receive follow-up communication via mHealth messages regarding HPV test results and support for triage and treatment within 12 months.

Follow-up via text messages and clinic visits as needed

Trial Site Locations

Total: 1 location

1

Kenyatta National Hospital

Nairobi, Kenya

Actively Recruiting

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Research Team

A

Agnes K Karume, MBChB, MBA, MPH

M

Millicent Masinde, MBChB, MMed, Fell.Gyn Oncology

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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