Actively Recruiting
Acceptability, Adherence, and Impact on the Bioavailability of Iron and Zinc of the Dietary Supplements Goodphyte IB Defense and Goodphyte Immunity in Adults With Chronic Diseases
Led by University of Thessaly · Updated on 2026-02-02
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate how well adult individuals with chronic diseases such as Crohn's disease, Ulcerative Colitis, Arterial Hypertension, Anemia, or Multiple Sclerosis accept and adhere to two dietary supplements containing microbial phytase, called Goodphyte IB Defense and Goodphyte Immunity. The study also investigates potential changes in the absorption of iron and zinc after phytase supplementation and how these changes might affect participants' quality of life. Participants will be randomly assigned to receive one of the two dietary supplements, Goodphyte IB Defense or Goodphyte Immunity. Each participant will take four capsules daily for two weeks. The study focuses on evaluating the acceptability and adherence to these supplements during this intervention period. Throughout the study, participants will complete questionnaires to assess acceptability and adherence immediately after the two-week intervention. Researchers will measure changes in serum iron, zinc, ferritin, inflammatory markers, quality of life, fatigue, body mass index, and disease-specific scores at baseline, mid-intervention, and after completion. The total participation lasts for two weeks, during which detailed clinical and quality of life evaluations will be made to understand the supplements' effects on these chronic conditions.
CONDITIONS
Brief Title
Acceptability, Adherence, and Impact on the Bioavailability of Iron and Zinc of the Dietary Supplements Goodphyte IB Defense and Goodphyte Immunity in Adults With Chronic Diseases.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Diagnosis of Crohn's disease in remission with stable pharmacological treatment for at least 3 months and stable dosage for the last month
- Diagnosis of Ulcerative colitis in remission with stable pharmacological treatment for at least 3 months and stable dosage for the last month
- Diagnosis of Hypertension with systolic blood pressure 130-139 mmHg or diastolic blood pressure 80-89 mmHg, controlled by lifestyle modifications without active symptoms or antihypertensive medication
- Diagnosis of Anemia with hemoglobin <12 g/dL (women) or <13 g/dL (men), serum iron <40 bcg/dL, and ferritin <15 ng/mL (women) or <30 ng/mL (men), absence of severe clinical consequences, and manageable fatigue, weakness, or dizziness
- Diagnosis of Multiple Sclerosis in remission with stable pharmacological treatment for at least 3 months and stable dosage for the last month
You will not qualify if you...
- Pregnancy or breastfeeding
- Current use of antibiotics or antibiotic use within the past month
- Current use of probiotic, prebiotic, or synbiotic supplements
- Current use of iron and/or zinc supplements
- Change in pharmacological treatment type within the past 3 months
- Change in pharmacological treatment dosage within the past month
- Renal or hepatic disease
- Inability to provide informed consent (including individuals under 18 years old)
- Insufficient understanding of the Greek language
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 2 weeks
Participants receive one of two dietary supplements, Goodphyte IB Defense or Goodphyte Immunity, by taking four capsules per day.
3 visits (baseline, mid-intervention at 1 week, and end of intervention at 2 weeks)
Trial Site Locations
Total: 1 location
1
School of Physical Education, Sport Science and Dietetics
Trikala, Thessaly, Greece, 42132
Actively Recruiting
Research Team
V
VAIOS SVOLOS, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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