Actively Recruiting

Phase 1
Phase 2
Age: 14Years - 21Years
All Genders
NCT05685368

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

Led by Children's Hospital Los Angeles · Updated on 2026-05-06

66

Participants Needed

1

Research Sites

221 weeks

Total Duration

On this page

Sponsors

C

Children's Hospital Los Angeles

Lead Sponsor

U

University of Southern California & Children's Hospital Los Angeles (USC-CHLA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The current study seeks to build on previous research that demonstrates the efficacy of Acceptance and Commitment Therapy in combating stigma by investigating the feasibility and acceptability of a protocol to support Black adolescents and young adults in coping with race related stress. The study will consist of a small, purposeful, non-randomized sample (N = 30) of clients enrolled into a 10-session Acceptance and Commitment Therapy group. The group will be offered as part of regular clinical care at the Division of Adolescent and Young Adult Medicine. Three consecutive groups will be run with approximately 8-10 participants in each group over the next year.

CONDITIONS

Official Title

Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

Who Can Participate

Age: 14Years - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be an adolescent or young adult aged 14 to 21 years
  • Have sickle cell disease
  • Willing to enroll in the Acceptance and Commitment Therapy (ACT) group at the Division of Adolescent and Young Adult Medicine/Department of Hematology and Oncology
  • Can be active, waitlisted, or new patients at CHLA
  • Able to understand and speak English
  • Have an English-speaking parent or guardian
  • Able to provide consent or assent
  • If pregnant, able to provide consent
  • Developmentally typical
  • Have a stable internet connection with webcam access and a private space for group sessions
  • Agree to audio and video recording of the initial interview
  • Agree to attend 6 weekly ACT group sessions
  • Willing to participate as a member of the community advisory board (CAB) if selected
Not Eligible

You will not qualify if you...

  • Prisoners or youth in detention centers
  • Unable to understand or speak English
  • Do not have sickle cell disease
  • At significant risk for suicide or self-injury
  • Adolescents with families requiring frequent intervention from the Department of Children and Family Services
  • Currently experiencing psychosis
  • Have severe health concerns impacting participation or attendance

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Children's Hospital Los Angeles

Los Angeles, California, United States, 90027

Actively Recruiting

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Research Team

X

Xzania Lee, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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