Actively Recruiting

Phase Not Applicable
Age: 18Years - 49Years
All Genders
NCT06819904

Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) RCT

Led by University of Pittsburgh · Updated on 2026-05-05

250

Participants Needed

2

Research Sites

126 weeks

Total Duration

On this page

Sponsors

U

University of Pittsburgh

Lead Sponsor

U

United States Department of Defense

Collaborating Sponsor

AI-Summary

What this Trial Is About

The primary objective of this multi-site randomized clinical trial (RCT) is to compare Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) with usual care vestibular rehabilitation (VESTIB CONTROL) in 250 individuals with mTBI-related vestibular symptoms attributable to mild traumatic brain injury (mTBI) treated at one of two sites (1) the University of Pittsburgh Medical Center, or (2) the Intrepid Spirit Center, Carl R. Darnall Army Medical Center, Fort Hood, Texas. Both interventions will be delivered weekly over 4 weeks. Assessments will be administered prior to the start of treatment (Baseline) and at 4-weeks, 3- and 6-months following the completion of treatment.

CONDITIONS

Official Title

Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) RCT

Who Can Participate

Age: 18Years - 49Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 to 49 years of age
  • Normal or corrected vision
  • Diagnosed with mild traumatic brain injury (mTBI) per military clinical guidelines that occurred more than 8 days before consent
  • Reported or observed signs of mTBI such as loss of consciousness, amnesia, disorientation, dizziness, imbalance, memory problems, or vomiting at injury time
  • Positive for mTBI-related vestibular symptoms or impairments shown by specific vestibular tests (DVAT, DNRS, VVAS, VOMS, mBESS, CP-Screen)
Not Eligible

You will not qualify if you...

  • History of vestibular disorders like benign paroxysmal positional vertigo or vestibular hypofunction
  • Exercise-induced dizziness
  • History of neurological disorders such as epilepsy or multiple sclerosis
  • Cervical spine injury or limited neck range of motion
  • Previous moderate to severe traumatic brain injury
  • Less than 8 days since current mTBI
  • Currently pregnant

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

University of Pittsburgh Concussion Research Laboratory

Pittsburgh, Pennsylvania, United States, 15213-4512

Actively Recruiting

2

Intrepid Spirit Center, Carl R. Darnall Army Medical Center

Fort Hood, Texas, United States, 76544

Not Yet Recruiting

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Research Team

A

Anthony Kontos, PhD

CONTACT

C

Courtney Perry, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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