Improving Cervical Cancer Screening and Treatment for Women Living with HIV in Nigeria Using Enhanced Implementation Strategies

What this Trial Is About

Researchers are evaluating ways to improve cervical cancer screening and treatment among women living with HIV WLHIV in Nigeria, a country with a large population affected by HIV and high rates of cervical cancer deaths. This study compares two sets of strategies to integrate cervical cancer services into existing HIV care programs, aiming to enhance screening, treatment, referral completion, and retention in care. The goal is to improve health outcomes and life expectancy for WLHIV facing both HIV and cervical cancer. The trial involves two groups receiving different implementation strategies. One group follows Core Implementation Strategies including ongoing consultation, educational meetings, strengthening referral systems, and preparing patients to participate actively. The other group receives these Core strategies plus enhanced approaches like community engagement through the Health Beginning Initiative Model and the use of Smart Cards to support patient involvement. The study uses a cluster randomized design to compare these approaches. Participants are women living with HIV aged 25 to 64 years. Researchers will monitor how well the cervical cancer screening and treatment services reach patients and how sustainable these services are over time. Outcomes include measuring reach at 12 months after enrollment and sustainment near study completion, along with assessing cervical cancer screening and treatment effectiveness 15 months after treating pre-invasive cancer. The study will track participant progress and service delivery throughout the study period ending in 2027.

ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services