Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT06422455

Access to Genetic Testing in Underserved Patients With Cancer

Led by University of Southern California · Updated on 2026-03-18

800

Participants Needed

2

Research Sites

261 weeks

Total Duration

On this page

Sponsors

U

University of Southern California

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study compares the experiences of people who receive information about genetic testing from a computer-generated character to patients who receive information from a human genetics healthcare provider. Patients with cancer are increasingly recommended for genetic testing as standard of care. Multiple factors contribute to low usage of genetic testing but for many patients the lack of access to genetic counseling and testing is an important and flexible factor. Lack of access is especially relevant to racial/ethnic minority patients and those living in non-metropolitan rural settings who are frequently cared for at safety-net hospitals with limited genetics services. Alternative delivery models are necessary to improve rates of access to genetic testing in patients with cancer. Health information technology is under used by genetics providers. A patient-facing relational agent (PERLA) will provide pre-test genetics education in both English and Spanish across two clinical settings to facilitate more timely access to genetic testing. Using the PERLA intervention may help researchers learn different ways to provide education about genetic testing to patients with cancer compared to usual care.

CONDITIONS

Official Title

Access to Genetic Testing in Underserved Patients With Cancer

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age > 18 years old
  • Diagnosed with at least one of the following cancers: epithelial ovarian cancer, exocrine pancreatic cancer, metastatic or high or very high-risk prostate cancer, breast cancer at or before age 50, bilateral breast cancer, triple negative breast cancer, or male breast cancer
  • Healthcare provider who treats patients with any of the above types of cancer
  • Able to read and write in English or Spanish
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Patients who cannot provide informed consent
  • Patients who cannot see, read, or write
  • Patients who have the cancer and clinical characteristics defined in the inclusion criteria but do not speak English or Spanish
  • Patients with none of the listed cancer diagnoses and clinical characteristics
  • Healthcare providers who do not treat cancer patients

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

USC / Norris Comprehensive Cancer Center

Los Angeles, California, United States, 90033

Actively Recruiting

2

University of Rochester

Rochester, New York, United States, 14642

Actively Recruiting

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Research Team

C

Charite Ricker, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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