Scientific Study on Factors Affecting Postoperative Delirium in Patients Aged 70 and Older

What this Trial Is About

This research aims to deepen understanding of how various factors relate to the development of postoperative delirium in older patients. It focuses on exploring delirium rates and examining links between internal body clock timing, heart rate variability, and delirium occurrence. The study includes patients from the QC-POD sample, aiming to clarify associations that may influence postoperative outcomes. The project evaluates multiple measures including internal circadian time chronotype, sleep parameters, perioperative heart rate variability, and peripheral cholinesterase activity. It also investigates intraoperative EEG patterns and core body temperature during surgery to explore their relationships with postoperative delirium. Data collection spans before, during, and after surgery with various monitoring techniques. Participants will be monitored up to five days after surgery for delirium incidence and followed through their hospital stay, averaging about seven days. Assessments include chronotype evaluations up to three months, heart rate variability and sleep monitoring until the third postoperative day, and EEG recordings during surgery. Researchers will evaluate delirium duration, body temperature, and insomnia severity as part of comprehensive outcome measurements.

Accompanying Scientific Program for the Quality Contract Prevention of Postoperative Delirium in the Care of Older Patients (WB-QC-POD)