Actively Recruiting
Scientific Program Studying Prevention of Postoperative Delirium in Older Patients Observing Sleep, Heart Rate, and Body Temperature Changes Around Surgery
Led by Charite University, Berlin, Germany · Updated on 2025-01-23
100
Participants Needed
1
Research Sites
114 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the development of postoperative delirium in older patients, focusing on how various factors like internal body clock rhythms and heart rate variability may influence its occurrence. This study is conducted as part of a scientific program alongside the Quality Contract Prevention of Postoperative Delirium (QC-POD) study, aiming to deepen understanding of delirium rates and related secondary outcomes. The project will explore multiple aspects including the patients' internal circadian time or chronotype, sleep patterns, perioperative heart rate variability, and peripheral cholinesterase activity around the time of surgery. It will also analyze the relationship between intraoperative EEG patterns, core body temperature, and the development of postoperative delirium. The study involves patients from the QC-POD study sample. Participants will be monitored for delirium incidence up to five days after surgery. Researchers will collect and analyze data related to heart rate variability, EEG signatures, body temperature, and other sleep-related parameters. The study focuses on patients aged 70 and older who have undergone elective or non-elective surgery, with assessments to better understand factors associated with postoperative delirium.
CONDITIONS
Official Title
Accompanying Scientific Program for the Quality Contract Prevention of Postoperative Delirium in the Care of Older Patients (WB-QC-POD)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 65 70 years
- Male and female patients
- Patients who have been included in QC-POD
- Eligible patients for inclusion: informed consent by the patient, preoperatively with verbal and written informed consent before the start of data collection
- Incapacitated patients for inclusion: Written informed consent by a legal representative
- Surgery (elective and not elective)
You will not qualify if you...
- Moribund patients (palliative situation)
- Insufficient knowledge of the German language
- Cardiac arrhythmia (e.g. atrial fibrillation)
- Presence of a pacemaker
- Condition after heart transplantation
- Inflammation in the area of the frontal sinus
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Anaesthesiology and Intensive Care Medicine, Campus Virchow-Klinikum (CVK) and Campus Charite Mitte (CCM), Charite - Universitätsmedizin Berlin
Berlin, Germany, 13353
Actively Recruiting
Research Team
C
Claudia Spies, MD, Prof.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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