Actively Recruiting
Accompanying Scientific Program for the Quality Contract Prevention of Postoperative Delirium in the Care of Older Patients (WB-QC-POD)
Led by Charite University, Berlin, Germany · Updated on 2025-01-23
100
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to deepen understanding of how various factors relate to the development of postoperative delirium in older patients. It focuses on exploring delirium rates and examining links between internal body clock timing, heart rate variability, and delirium occurrence. The study includes patients from the QC-POD sample, aiming to clarify associations that may influence postoperative outcomes. The project evaluates multiple measures including internal circadian time (chronotype), sleep parameters, perioperative heart rate variability, and peripheral cholinesterase activity. It also investigates intraoperative EEG patterns and core body temperature during surgery to explore their relationships with postoperative delirium. Data collection spans before, during, and after surgery with various monitoring techniques. Participants will be monitored up to five days after surgery for delirium incidence and followed through their hospital stay, averaging about seven days. Assessments include chronotype evaluations up to three months, heart rate variability and sleep monitoring until the third postoperative day, and EEG recordings during surgery. Researchers will evaluate delirium duration, body temperature, and insomnia severity as part of comprehensive outcome measurements.
CONDITIONS
Brief Title
Accompanying Scientific Program for the Quality Contract Prevention of Postoperative Delirium in the Care of Older Patients (WB-QC-POD)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 70 years or older
- Male and female patients
- Patients who have been included in QC-POD
- Able to give informed consent personally or via a legal representative if incapacitated
- Undergoing elective or emergency surgery
You will not qualify if you...
- Moribund patients in palliative care
- Insufficient knowledge of the German language
- Cardiac arrhythmia such as atrial fibrillation
- Presence of a pacemaker
- History of heart transplantation
- Inflammation near the frontal sinus
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 3 days post surgery
Participants undergo assessments including bodytime, chronotype, and sleep monitoring before and shortly after surgery, as well as intraoperative measurements such as electroencephalography and heart rate variability.
Assessments during surgery and daily visits up to 3 days post surgery
Duration - Up to 3 months
Participants are followed up to monitor the incidence and duration of postoperative delirium, heart rate variability, and insomnia severity index after hospital discharge.
Regular follow-up visits up to 3 months
Trial Site Locations
Total: 1 location
1
Department of Anaesthesiology and Intensive Care Medicine, Campus Virchow-Klinikum (CVK) and Campus Charite Mitte (CCM), Charite - Universitätsmedizin Berlin
Berlin, Germany, 13353
Actively Recruiting
Research Team
C
Claudia Spies, MD, Prof.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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