Non-Invasive Liver Disease Evaluation Using LiverScope4 Compared to Advanced MR Exams in Adults With MASLD

What this Trial Is About

Researchers are evaluating new techniques to non-invasively assess liver disease, focusing on a condition called MASLD, also known as NAFLD. This study is the second phase of a project testing a new LiverScope4 device, which is a small, portable MR-based tool designed to evaluate the liver. The goal is to compare LiverScope4 measurements to those from advanced conventional liver MR exams, which are commonly used to monitor MASLD. LiverScope4 is not yet approved for clinical use. All participants will undergo the same research procedures in this single-arm study. They will have a LiverScope4 exam that measures liver proton density fat fraction and other exploratory values, as well as an advanced MR exam to measure similar liver features and stiffness. Additional procedures include an optional FibroScan exam, a blood draw for routine lab tests, body measurements, and completion of questionnaires covering demographics and medical history. Participants will complete a one-time visit involving all these procedures, including liver imaging, blood sampling, and questionnaires. Researchers will assess how well LiverScope4 measurements agree with conventional MR results and evaluate the repeatability and consistency of LiverScope4 over up to three months. The study aims to provide detailed comparisons and monitor measurement reliability in people with MASLD.

Accurate Point of Care Liver Disease Diagnostics (Phase 2)