Actively Recruiting
Accurate Point of Care Liver Disease Diagnostics
Led by University of California, San Diego · Updated on 2026-04-09
26
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of California, San Diego
Lead Sponsor
L
Livivos, Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating new techniques to non-invasively assess liver disease, focusing on a condition called MASLD, also known as NAFLD. This study is the second phase of a project testing a new LiverScope4 device, which is a small, portable MR-based tool designed to evaluate the liver. The goal is to compare LiverScope4 measurements to those from advanced conventional liver MR exams, which are commonly used to monitor MASLD. LiverScope4 is not yet approved for clinical use. All participants will undergo the same research procedures in this single-arm study. They will have a LiverScope4 exam that measures liver proton density fat fraction and other exploratory values, as well as an advanced MR exam to measure similar liver features and stiffness. Additional procedures include an optional FibroScan exam, a blood draw for routine lab tests, body measurements, and completion of questionnaires covering demographics and medical history. Participants will complete a one-time visit involving all these procedures, including liver imaging, blood sampling, and questionnaires. Researchers will assess how well LiverScope4 measurements agree with conventional MR results and evaluate the repeatability and consistency of LiverScope4 over up to three months. The study aims to provide detailed comparisons and monitor measurement reliability in people with MASLD.
CONDITIONS
Brief Title
Accurate Point of Care Liver Disease Diagnostics (Phase 2)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Known or clinically suspected MASLD
- Body mass index (BMI) greater than 27 kg/m² and less than 45 kg/m² at time of referral
- Ability to lie on the LiverScope® device table for about 60 minutes
- Ability to hold breath repeatedly for about 20 seconds during MR and LiverScope® exams
- Willing and able to undergo all study procedures
You will not qualify if you...
- UCSD or Livivos study personnel
- Contraindications to MR
- Pregnant, possibly pregnant, or trying to become pregnant
- Known chronic liver disease other than MASLD
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 3 months
Participants undergo LiverScope® and advanced MR examinations, blood draws, body measurements, and questionnaires to assess liver disease status and related health information.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
University of California San Diego
La Jolla, California, United States, 92037
Actively Recruiting
Research Team
Y
Yesenia Covarrubias
G
Gage Tanzman
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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