Actively Recruiting
Acellular Dermal Matrix vs Autologous Tarsus for Correction of Lower Eyelid Retraction
Led by Haukeland University Hospital · Updated on 2025-04-17
40
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the effectiveness of two promising implants in treatment of lower eyelid retraction in 40 patients. This condition often resulting from injury, surgical complications, or thyroid eye disease. The main questions it aims to answer are: Which implant provides better long-term stability of the eyelid malposition? Does one implant minimize complications and improve patient outcomes more effectively than the other? This study will compare the use of donor sclera implants to a cellular dermal matrix to see if either offers superior results in terms of reducing graft shrinkage and improving eyelid positioning. Participants will: Undergo lower eyelid reconstruction surgery with one of the two implants. Be monitored for postoperative outcomes, including eyelid position, recurrence rates, and complications over a follow-up period 6 months.
CONDITIONS
Official Title
Acellular Dermal Matrix vs Autologous Tarsus for Correction of Lower Eyelid Retraction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients aged 18-75 years
- Grade 2 or higher lower eyelid retraction
- Candidate for surgical correction due to functional or cosmetic reasons
- Willingness to participate and provide informed consent
You will not qualify if you...
- Active ocular or eyelid infection
- History of severe scarring or keloid formation
- Concurrent orbital or eyelid malignancies
- Pregnancy or lactation
- Uncontrolled systemic diseases such as diabetes or immune disorders
- Previous eyelid surgery on the affected eye
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Haukeland University Hospital
Bergen, Vetslandet, Norway, 5021
Actively Recruiting
Research Team
H
Hans Olav Ueland, MD, PhD
CONTACT
A
Annette Morwena Hope, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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