Actively Recruiting

All Genders
NCT07330245

Achievement of LLDAS5 in Patients With Systemic Lupus Erythematosus Treated With Anifrolumab.

Led by AstraZeneca · Updated on 2026-04-29

218

Participants Needed

19

Research Sites

143 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is an observational, multicenter, prospective study on patients with systemic lupus erythematosus treated with anifrolumab in Italy aimed at evaluating the achievement of LLDAS5

CONDITIONS

Official Title

Achievement of LLDAS5 in Patients With Systemic Lupus Erythematosus Treated With Anifrolumab.

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Provided informed consent to participate in the study
  • Aged 18 years or older
  • Fulfilled the 2019 EULAR/ACR classification criteria for SLE at the time of study entry
  • Prescribed anifrolumab for SLE treatment for the first time according to approved Italian label and reimbursement criteria
Not Eligible

You will not qualify if you...

  • Patients who are at LLDAS5 at the time of study entry
  • Previous exposure to anifrolumab
  • Documented diagnosis of severe or rapidly progressive Class III or IV glomerulonephritis requiring induction therapy (mycophenolate mofetil or cyclophosphamide plus high dose steroids), isolated Class V lupus nephritis, or active severe or unstable neuropsychiatric lupus
  • Currently participating in any interventional clinical trial with an investigational product
  • Inability to understand and sign the informed consent and to fill in patient questionnaires

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 19 locations

1

Azienda Ospedaliero-Universitaria di Cagliari Presidio di Monserrato

Monserrato, CA, Italy, 09032

Not Yet Recruiting

2

Azienda Ospedaliero-Universitaria di Ferrara Arcispedale Sant'Anna

Cona, Ferrara, Italy, 44124

Actively Recruiting

3

IRCCS Humanitas Research Hospital

Rozzano, Milano, Italy, 20089

Not Yet Recruiting

4

AOU Ospedali Riuniti di Ancona - Presidio Torrette

Ancona, Italy, 60126

Not Yet Recruiting

5

Azienda Ospedaliero-Universitaria Policlinico di Bari

Bari, Italy, 70124

Not Yet Recruiting

6

ASST Spedali Civili di Brescia

Brescia, Italy, 25123

Not Yet Recruiting

7

Azienda Ospedaliero-Universitaria Careggi

Florence, Italy, 50134

Not Yet Recruiting

8

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Italy, 20122

Not Yet Recruiting

9

Policlinico di Modena - AOU di Modena

Modena, Italy, 41124

Not Yet Recruiting

10

Azienda Ospedaliera di Padova

Padova, Italy, 35128

Not Yet Recruiting

11

Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone"

Palermo, Italy, 90127

Not Yet Recruiting

12

Fondazione IRCCS Policlinico San Matteo

Pavia, Italy, 27100

Not Yet Recruiting

13

Azienda Ospedaliero-Universitaria Pisana Ospedale Santa Chiara

Pisa, Italy, 56126

Not Yet Recruiting

14

Policlinico Tor Vergata

Roma, Italy, 00133

Not Yet Recruiting

15

Policlinico Umberto I - Sapienza Università di Roma

Roma, Italy, 00161

Not Yet Recruiting

16

Azienda Ospedaliera Ordine Mauriziano Umberto I

Torino, Italy, 10128

Not Yet Recruiting

17

Azienda Sanitaria Universitaria Giuliano Isontina (ASU GI) - Ospedale di Cattinara

Trieste, Italy, 34128

Not Yet Recruiting

18

ASU Friuli Centrale - Ospedale Santa Maria della Misericordia di Udine

Udine, Italy, 33100

Not Yet Recruiting

19

AOUI Verona - Ospedale Borgo Roma

Verona, Italy, 37134

Not Yet Recruiting

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Research Team

A

AstraZeneca Clinical Study Information Center

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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