Actively Recruiting
Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer
Led by EXACT Therapeutics AS · Updated on 2026-04-03
25
Participants Needed
10
Research Sites
108 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer.
CONDITIONS
Official Title
Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Not deemed suitable for primary curative surgery and have radiographic and pathological disease consistent with inoperable LAPC or borderline resectable pancreatic cancer.
- Suitable to receive treatment with mFOLFIRINOX according to the Investigator's assessment.
You will not qualify if you...
- Any prior anti-cancer treatment for pancreatic cancer (e.g. chemotherapy, surgery, radiation). Palliative bypass procedure and bile duct stenting are allowed.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 10 locations
1
HonorHealth Research Institute
Scottsdale, Arizona, United States, 85258
Actively Recruiting
2
Stanford Cancer Center Palo Alto
Stanford, California, United States, 94305
Actively Recruiting
3
Beth Israel Deaconess Medical Center - Division of Hematology/Oncology
Boston, Massachusetts, United States, 02215
Actively Recruiting
4
Henry Ford Centre
Detroit, Michigan, United States, 48202
Actively Recruiting
5
Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
6
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States, 15212
Actively Recruiting
7
Brown University Cancer Institute
Providence, Rhode Island, United States, 02906
Actively Recruiting
8
CAMBRIDGE CANCER TRIALS CENTRE-Addenbrooke's Hospital
Cambridge, Cambridge, United Kingdom, CB2 0QQ
Actively Recruiting
9
Gary Weston Centre- Imperial College Healthcare- Du Cane Road
Hammersmith, London, United Kingdom, W12 0HS
Actively Recruiting
10
The Royal Marsden- Downs Road
Sutton, Surrey, United Kingdom, SM2 5PT
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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