Actively Recruiting
Acoustics as a Metric of Airway Pressure in Premature Infants Using Bubble Continuous Positive Airway Pressure
Led by McGill University Health Centre/Research Institute of the McGill University Health Centre · Updated on 2026-03-30
30
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
Sponsors
M
McGill University Health Centre/Research Institute of the McGill University Health Centre
Lead Sponsor
N
Northwestern University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is an observational, proof-of-concept, feasibility study where 30 preterm infants on bubble CPAP with gestational age \< 32+0 weeks will be recruited from the neonatal intensive care unit (NICU) at the Montreal Children's Hospital. The study's main goals are: 1. To determine the relationship between ambient bubbling sounds and delivered pressures in preterm infants on bCPAP. 2. To determine the relationship between transmitted bubbling sounds and airway pressures transmitted to the lungs of preterm infants on bCPAP. 3. To develop models to predict delivered and transmitted bCPAP pressures from the acoustic properties of bubbling sounds.
CONDITIONS
Official Title
Acoustics as a Metric of Airway Pressure in Premature Infants Using Bubble Continuous Positive Airway Pressure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Infants on bubble CPAP with gestational age less than 32 weeks
- Postmenstrual age between 28 weeks 0 days and 36 weeks 6 days at study time
- Postnatal age greater than 168 hours (7 days) at study time
- Receiving bubble CPAP via binasal prongs at study time
- Bubble CPAP pressure levels between 5 and 7 cm H2O with gas flow between 6 and 10 L/min at study time
You will not qualify if you...
- Known major congenital anomalies
- Known congenital heart disorders
- Known neuromuscular disease
- Receiving ventilator-derived CPAP at study time
- Receiving CPAP via nasal mask interface at study time
- Receiving inotropes, narcotics or sedative agents at study time
- Clinically unstable as determined by attending neonatologist
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
McGill University Health Center
Montreal, Quebec, Canada, H4A 3J1
Actively Recruiting
Research Team
W
Wissam Shalish, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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