Actively Recruiting
Acquired Dyslexia Modeling and Treatment
Led by Rutgers, The State University of New Jersey · Updated on 2026-05-06
12
Participants Needed
3
Research Sites
38 weeks
Total Duration
On this page
Sponsors
R
Rutgers, The State University of New Jersey
Lead Sponsor
N
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is a low-risk, early phase 1, multicenter trial to test the use of a computational (neural network) cognitive model of reading to simulate acquired dyslexia and its treatment. The aim is to determine whether there is an advantage to receiving the treatment the model predicts to be advantageous compared to the alternative treatment. All participants will receive two full rounds of treatment. A round of treatment will consist of either phonomotor treatment (PMT) or semantic feature analysis (SFA) for 60 hours, distributed over 5 days a week for 2 hours a day.
CONDITIONS
Official Title
Acquired Dyslexia Modeling and Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fluent in English as a first language before stroke by self report
- Normal or corrected-to-normal vision
- Normal or aided hearing
- Left hemisphere ischemic or hemorrhagic stroke confirmed by a brain scan
- Impaired reading as shown by significant impairment in the Basic Skills cluster of the Woodcock Reading Mastery Test - III
You will not qualify if you...
- Diagnosed neurological disease affecting the brain before stroke other than left hemisphere stroke
- Severe apraxia of speech determined by speech-language pathologists
- History of learning disabilities such as developmental dyslexia
- Current self-reported major psychiatric disorders
- Inability to undergo or provide a post-stroke brain imaging scan
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Florida State University
Tallahassee, Florida, United States, 32306
Actively Recruiting
2
Johns Hopkins University School of Medicine
Baltimore, Maryland, United States, 21287
Actively Recruiting
3
Kessler Foundation
West Orange, New Jersey, United States, 07052
Actively Recruiting
Research Team
W
William W Graves, PhD
CONTACT
O
Olga Boukrina, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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