Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06352632

ACT-GLOBAL Adaptive Platform Trial for Stroke

Led by The George Institute · Updated on 2024-11-21

20000

Participants Needed

2

Research Sites

518 weeks

Total Duration

On this page

Sponsors

T

The George Institute

Lead Sponsor

U

University of Calgary

Collaborating Sponsor

AI-Summary

What this Trial Is About

Stroke is causing 6.6 million deaths and is a major cause of disability worldwide in 2019. There remains an urgent need for interventions that improve outcomes which can be implemented with wide applicability for stroke. ACT-GLOBAL is a multi-factorial, multi-arm, multi-stage, randomised, global adaptive platform trial for stroke, aiming to identify the treatment/s associated with the highest chance of improving outcome in stroke patients. In ACT-GLOBAL multiple questions will be evaluated simultaneously and sequentially as data accrues and can evaluate interactions between different treatment options.

CONDITIONS

Official Title

ACT-GLOBAL Adaptive Platform Trial for Stroke

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Clinical diagnosis of stroke
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 2 locations

1

The George Institute for Global Health

Sydney, New South Wales, Australia, 2005

Actively Recruiting

2

University of Calgary

Calgary, Alberta, Canada, T2N 1N4

Actively Recruiting

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Research Team

X

Xiaoying Chen, PhD

CONTACT

B

Bijoy Menon, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

FACTORIAL

Primary Purpose

TREATMENT

Number of Arms

4

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