Actively Recruiting
ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder
Led by Beny Lafer · Updated on 2025-04-03
42
Participants Needed
1
Research Sites
134 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to test the efficacy of Acceptance and Commitment Therapy (ACT) as a psychotherapeutic treatment for patients with Bipolar Disorder (BD). The following questions will be investigated: * The efficacy of ACT in reducing depressive symptoms in patients with BD. * The efficacy of ACT in improving the quality of life in patients with BD. * The efficacy of ACT in improving functionality in patients with BD. * The efficacy of ACT in improving sleep quality in patients with BD. * The efficacy of ACT in improving psychological flexibility in patients with BD Participants in the clinical group will undergo 12, 2 hours, weekly sessions of Acceptance and Commitment Therapy, in addition to their regular pharmacological treatment. Participants in the control group will undergo 3, 2 hours, weekly sessions of Bipolar Disorder Psychoeducation Therapy, in addition to their regular pharmacological treatment. Scales and assessments will be used to measure study outcomes on 5 different time-points: pre-intervention (month 0), post-intervention (month 3), follow-up 1 (month 6), follow-up 2 (month 9), follow-up 3 (month 12). Mood scales will be assessed every 2 weeks for the duration of treatment and every 4 weeks during the additional 12 week follow-up period. Results will be compared among both groups to assess the effectiveness of Acceptance and Commitment Therapy as an intervention for syndromic and sub-syndromic depression in bipolar disorder.
CONDITIONS
Official Title
ACT for Syndromic and Subsyndromic Depression in Bipolar Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Bipolar Disorder type I or II according to DSM V
- Presence of depressive symptoms with MADRS score greater than 12
- Not currently undergoing psychotherapy
- Availability to attend in-person group therapy sessions
- Signing consent form
You will not qualify if you...
- Organic mental disorder
- Presence of manic or hypomanic symptoms with YMRS score greater than 12
- Currently undergoing psychotherapy that cannot be paused during the study
- Major medication change in the last 30 days
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tatiana Cohab Khafif
São Paulo, São Paulo, Brazil, 01231010
Actively Recruiting
Research Team
B
Beny Lafer, MD PhD
CONTACT
T
Tatiana C Khafif, Master's degree
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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