Actively Recruiting

Phase Not Applicable
Age: 20Years - 30Years
All Genders
Healthy Volunteers
NCT04758754

Active and Passive Exercise Training in Improving Vascular Function: Local vs Systemic Vascular Effect.

Led by University of Milan · Updated on 2024-05-29

36

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

Sponsors

U

University of Milan

Lead Sponsor

U

Universita di Verona

Collaborating Sponsor

AI-Summary

What this Trial Is About

Maintaining an adequate state of vascular function is an important element for the maintenance of cardiovascular well-being. Several training plans involving both active and passive engagement by the muscles have been proposed with the aim of improving vascular function. At local level, i.e., at the level of the arteries that supply the muscles directly involved in training, significant improvements in vascular function have been found. These improvements are more noticeable after active training than with a passive training regimen, such as passive static stretching. On the contrary, at the systemic level the effects of active or passive training are less clear and, above all, it is not evident whether there is a difference in the effects induced at the level of vascular function in arteries supplying muscles not directly involved in training. The aim of the study is to clarify the local and systemic effect of an active training protocol (single leg knee extension, SLKE) and of a passive training protocol (passive static stretching training, PST) applied to the lower limbs lasting 8 weeks on the local (femoral artery) and systemic (brachial artery) vascular function.

CONDITIONS

Official Title

Active and Passive Exercise Training in Improving Vascular Function: Local vs Systemic Vascular Effect.

Who Can Participate

Age: 20Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

.

Not Eligible

You will not qualify if you...

  • Neurological, vascular, and musculoskeletal disorders of the lower and upper limbs
  • Use of medications affecting neural or vascular responses, including hormonal contraceptives and oral supplements
  • Current or former smoking
  • Irregular menstrual cycle (outside 26 to 35 days) within 3 months before the study
  • Contraindications to joint mobilization
  • Regular participation in single leg knee extension or passive stretching training programs

AI-Screening

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Trial Site Locations

Total: 1 location

1

Department of Biomedical Science for Health

Milan, Italy, 20133

Actively Recruiting

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Research Team

E

Emiliano Cè, PhD

CONTACT

S

Stefano Longo, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

3

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