Actively Recruiting
Active and Passive Exercise Training in Improving Vascular Function: Local vs Systemic Vascular Effect.
Led by University of Milan · Updated on 2024-05-29
36
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
Sponsors
U
University of Milan
Lead Sponsor
U
Universita di Verona
Collaborating Sponsor
AI-Summary
What this Trial Is About
Maintaining an adequate state of vascular function is an important element for the maintenance of cardiovascular well-being. Several training plans involving both active and passive engagement by the muscles have been proposed with the aim of improving vascular function. At local level, i.e., at the level of the arteries that supply the muscles directly involved in training, significant improvements in vascular function have been found. These improvements are more noticeable after active training than with a passive training regimen, such as passive static stretching. On the contrary, at the systemic level the effects of active or passive training are less clear and, above all, it is not evident whether there is a difference in the effects induced at the level of vascular function in arteries supplying muscles not directly involved in training. The aim of the study is to clarify the local and systemic effect of an active training protocol (single leg knee extension, SLKE) and of a passive training protocol (passive static stretching training, PST) applied to the lower limbs lasting 8 weeks on the local (femoral artery) and systemic (brachial artery) vascular function.
CONDITIONS
Official Title
Active and Passive Exercise Training in Improving Vascular Function: Local vs Systemic Vascular Effect.
Who Can Participate
Eligibility Criteria
You may qualify if you...
.
You will not qualify if you...
- Neurological, vascular, and musculoskeletal disorders of the lower and upper limbs
- Use of medications affecting neural or vascular responses, including hormonal contraceptives and oral supplements
- Current or former smoking
- Irregular menstrual cycle (outside 26 to 35 days) within 3 months before the study
- Contraindications to joint mobilization
- Regular participation in single leg knee extension or passive stretching training programs
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Trial Site Locations
Total: 1 location
1
Department of Biomedical Science for Health
Milan, Italy, 20133
Actively Recruiting
Research Team
E
Emiliano Cè, PhD
CONTACT
S
Stefano Longo, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
3
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