Actively Recruiting

Age: 18Years +
MALE
NCT05810467

The Active Surveillance Study

Led by Institute of Cancer Research, United Kingdom · Updated on 2026-02-04

200

Participants Needed

4

Research Sites

223 weeks

Total Duration

On this page

Sponsors

I

Institute of Cancer Research, United Kingdom

Lead Sponsor

R

Royal Marsden NHS Foundation Trust

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Active Surveillance study is a prospective study developed to look at the association of biomarkers with PrCa presentation and progression among men on Active Surveillance and stratify it by their genetic risk. This study will also investigate the incidence and progression by differing genetic risks.

CONDITIONS

Official Title

The Active Surveillance Study

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Men 18 years old or older under the care of an Active Surveillance clinic
  • Known diagnosis of prostate cancer deemed suitable for Active Surveillance by a multi-disciplinary team
  • Men at genetically higher prostate cancer risk defined by family history, ancestry, pathogenic gene mutations, or high genetic risk variants
  • Men without known high risk genetic factors diagnosed with low-grade prostate cancer and suitable for Active Surveillance
  • Performance status between 0 and 2
  • No psychological, familial, sociological, or geographical issues that could affect study compliance or follow-up
Not Eligible

You will not qualify if you...

  • No prostate cancer diagnosis
  • Prostate cancer not suitable for Active Surveillance as determined by a multi-disciplinary team
  • Significant psychological conditions that may worsen or be exacerbated by participation in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Institute of Cancer Research and Royal Marsden Hospital

Sutton, Surrey, United Kingdom, SM2 5PT

Actively Recruiting

2

North Bristol NHS Trust

Bristol, United Kingdom, BS10 5NB

Not Yet Recruiting

3

The Royal Marsden Hospital

London, United Kingdom, SW3 6JJ

Actively Recruiting

4

The Royal Marsden Hospital

Sutton, United Kingdom, SM2 5PT

Actively Recruiting

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Research Team

E

Eva McGrowder, PhD

CONTACT

E

Elizabeth K Bancroft, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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