Actively Recruiting
Acupuncture for Oxaliplatin-induced Peripheral Neuropathy in Gastro-intestinal Cancer Patients
Led by GERCOR - Multidisciplinary Oncology Cooperative Group · Updated on 2025-07-23
182
Participants Needed
5
Research Sites
210 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
ACUPOX is a multicenter, open label, 2-cohort based phase II clinical study evaluating the interest of a standardized protocol of verum acupuncture in treatment of Oxaliplatin-induced peripheral neuropathy in patients with gastro-intestinal solid tumors who discontinued oxaliplatin-containing chemotherapy.
CONDITIONS
Official Title
Acupuncture for Oxaliplatin-induced Peripheral Neuropathy in Gastro-intestinal Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Written informed consent given voluntarily
- Eastern Cooperative Oncology Group performance status of 0 to 2
- Histologically or cytologically confirmed gastro-intestinal solid tumors
- Previously treated with oxaliplatin-based chemotherapy
- Last oxaliplatin infusion more than 2 weeks before inclusion
- Peripheral neuropathy with a numerical rating score of 4 or higher at inclusion
- Currently receiving or recently completed chemotherapy excluding platinum salts and taxane-based regimens
- Able to understand and read French
- Registered in a national health care system (PUMa included)
You will not qualify if you...
- Received acupuncture for chemotherapy side effects within 3 months prior to inclusion
- Previous or current chemotherapy with taxane-based regimens
- Preexisting clinically significant peripheral neuropathy from causes other than chemotherapy
- History of recent (within 4 weeks) abuse of alcohol, prescription, or illicit drugs or other conditions affecting study compliance
- Any unstable condition that could affect safety or compliance during the study
- Limb edema grade 3 (CTCAE v5)
- Phytotherapy within 2 weeks before intervention
- Pregnant or breastfeeding
- Under tutorship, guardianship, or in custody of the justice system
AI-Screening
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Trial Site Locations
Total: 5 locations
1
Centre intercommunal de Créteil
Créteil, France
Not Yet Recruiting
2
Hôpital Henri Mondor
Créteil, France
Actively Recruiting
3
Institu Daniel Hollard
Grenoble, France
Not Yet Recruiting
4
Hôpital Pitié Salpêtrière
Paris, France
Not Yet Recruiting
5
Hôpital Saint Antoine
Paris, France
Actively Recruiting
Research Team
M
Marie Line GARCIA LARNICOL
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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