Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
NCT05267093

Acupuncture vs Sham Acupuncture for Hand Osteoarthritis

Led by Guang'anmen Hospital of China Academy of Chinese Medical Sciences · Updated on 2025-07-16

340

Participants Needed

1

Research Sites

240 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The investigators plan to conduct this multicentered, sham-controlled randomized clinical trial to evaluate the efficacy and safety of acupuncture for clinical symptomatic improvement of hand OA.

CONDITIONS

Official Title

Acupuncture vs Sham Acupuncture for Hand Osteoarthritis

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with hand osteoarthritis according to American College of Rheumatology criteria
  • History of hand osteoarthritis for at least 3 months before enrollment
  • History of taking nonsteroidal anti-inflammatory drugs (NSAIDs) for hand osteoarthritis
  • Aged between 18 and 80 years
  • Average pain intensity of at least 40 mm on visual analog scale in the dominant hand over last 48 hours
  • Increase in pain of at least 20 mm after 1-week NSAID washout if currently using NSAIDs
  • X-rays of dominant hand showing Kellgren-Lawrence grade 1, 2, or 3 changes in symptomatic joints
  • Negative rheumatoid factor and anticyclonic citrullinated peptide test results
  • Able to follow the study protocol and understand medical information
  • Willing to sign informed consent
Not Eligible

You will not qualify if you...

  • History or evidence of secondary osteoarthritis or symptomatic osteoarthritis in other locations requiring treatment
  • History of inflammatory arthritis (such as rheumatoid or psoriatic arthritis), hemochromatosis, metabolic, or neuropathic arthropathies
  • Hand or arm trauma, dislocation, or surgery within the past 3 months
  • Hand pain or stiffness due to tissue scarring or tendinitis
  • Serious skin damage or disorders on the hands
  • Use of antidepressants, anticonvulsants, vascular drugs, or narcotics within 10 days before study start
  • Use of corticosteroids or hyaluronic acid injections within 3 months before enrollment
  • Serious uncontrolled medical conditions like cancer, cardiovascular disorder, severe liver/kidney problems, or blood clotting disorders
  • Fear of acupuncture or having received acupuncture treatment within 4 weeks before enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences Guang'anmen Hospital

Beijing, China

Actively Recruiting

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Research Team

W

Weiming Wang, Ph.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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