Actively Recruiting
Acute Agitation in Emergency Psychiatry
Led by Lone Baandrup · Updated on 2025-01-01
132
Participants Needed
1
Research Sites
152 weeks
Total Duration
On this page
Sponsors
L
Lone Baandrup
Lead Sponsor
U
University Hospital Bispebjerg and Frederiksberg
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of the study is to improve the pharmacological treatment of psychiatric patients with acute agitation.
CONDITIONS
Official Title
Acute Agitation in Emergency Psychiatry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 18 to 64 years
- Agitation requiring tranquilization in inpatient psychiatric settings including emergency rooms
- Total score of at least 14 on the PANSS Excited Component (PEC)
- A score of 4 or higher on at least one of the five PEC items
- Informed consent given before the emergency occurs
You will not qualify if you...
- Involuntary psychiatric admission under the Danish Mental Health Act
- Female patients who are breastfeeding
- Females under 50 years who cannot confirm a negative pregnancy test and safe contraceptive use
- Body weight less than 50 kg
- Extreme obesity with body mass index of 40 kg/m2 or higher
- Situations where antipsychotic drugs are preferred for acute agitation treatment
- Unwillingness or inability to cooperate with study procedures
- Insufficient language skills to read, write, or provide informed consent in Danish or other available languages
- Suspected contraindications for any treatment arms
- Use of benzodiazepines, sedatives, or antipsychotics within 4 hours before study treatment
- Known allergy to any study medications
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mental Health Center Copenhagen, Bispebjerg
Copenhagen N, Denmark, 2400
Actively Recruiting
Research Team
L
Lone Baandrup, MD, DMSc
CONTACT
M
Marie Vang Jensen, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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