Actively Recruiting

Phase Not Applicable
Age: 18Years - 50Years
All Genders
Healthy Volunteers
NCT07210411

Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury

Led by Mayo Clinic · Updated on 2026-03-09

80

Participants Needed

1

Research Sites

264 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this research is to learn about how the participant's body is able to balance changes in blood pressure, and how spinal cord stimulation affects these changes as well as immune \& cardiovascular function in participants with spinal cord injury.

CONDITIONS

Official Title

Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury

Who Can Participate

Age: 18Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 50 years
  • Spinal cord injury classified as American Spinal Injury Association Impairment Scale A-D
  • Neurological injury level between C6 and T8 as defined by international standards
  • Injury occurred more than six months ago
  • Includes individuals with and without implanted epidural spinal cord stimulators
  • Includes twenty uninjured control participants
Not Eligible

You will not qualify if you...

  • History of cardiovascular disease, diabetes, autonomic neuropathies, neurological disorders (except spinal cord injury), or current smoking
  • Taking beta blockers, antihypertensives, or other sympathically active medications that cannot be stopped
  • Pregnant or lactating women
  • Cognitive impairments preventing informed consent
  • Body mass index greater than 30 kg/m2 for uninjured controls
  • Taking medications that may interact adversely with phenylephrine
  • Any illness or condition that may interfere with study compliance, safety, or result interpretation as judged by the principal investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

Z

Zachary Pohlkamp

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

3

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Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury | DecenTrialz