Actively Recruiting
Acute Effects of Cold Exposure on Cardiovascular System
Led by Fudan University · Updated on 2025-02-27
40
Participants Needed
1
Research Sites
115 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a randomized controlled human exposure crossover study. Investigators aim to assess the acute effects of low temperature exposure on cardiovascular system and the underlying mechanisms.
CONDITIONS
Official Title
Acute Effects of Cold Exposure on Cardiovascular System
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Living in Shanghai during the study period
- Body mass index > 18.5 and 3c 28
- Right-handed
- Receiving or having received higher education
- With the ability to read and understand Chinese smoothly
You will not qualify if you...
- Smoking and alcohol abuse
- Current drug and dietary supplements intake
- Subjects with allergic diseases, such as allergic rhinitis, allergic asthma, and atopy
- Subjects with cardiovascular diseases, such as congenital heart disease, pulmonary heart disease, and hypertension
- Subjects with respiratory diseases, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease
- Subjects with chronic diseases, such as diabetes, chronic hepatitis, and kidney disease
- Subjects who have a history of major surgery due to cardiovascular, cerebrovascular, respiratory, or neurological diseases
- Subjects with neurologic disorders, such as stroke, traumatic brain injury, epilepsy, and schizophrenia
- Abnormal spirometry (FEV1 and FVC 3c 75% of predicted and FEV1/FVC 3c 0.65)
- Subjects with color vision disabilities
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Environmental Health, School of Public Health, Fudan University
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
Research Team
R
Renjie Chen, PhD
CONTACT
H
Haidong Kan, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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