Actively Recruiting

Phase Not Applicable
Age: 20Years - 45Years
FEMALE
Healthy Volunteers
NCT06868862

Acute Effects of Isoenergetic HIIE Vs. MICE on Key Parameters of Fat Mass Loss in Young Females with Overweight or Obesity

Led by Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques · Updated on 2025-03-11

15

Participants Needed

1

Research Sites

47 weeks

Total Duration

On this page

Sponsors

L

Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques

Lead Sponsor

L

LAPEF laboratory, Sao paulo

Collaborating Sponsor

AI-Summary

What this Trial Is About

Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases. Managing obesity effectively requires lifestyle and dietary modifications, including increased physical activity. Among the various exercise strategies, Moderate-Intensity Continuous Training (MICT) and High-Intensity Interval Training (HIIT) are widely recommended for reducing FM. Compared to MICT, HIIT is a time-efficient approach, often perceived as more enjoyable, and has been shown to promote greater total and abdominal fat loss in a shorter period. However, the precise mechanisms underlying this enhanced fat loss remain unclear. This study aims to compare the acute effects of two isoenergetic exercise sessions - MICE (Moderate-Intensity Continuous Exercise) and HIIE (High-Intensity Interval Exercise) - on key physiological responses involved in fat mass loss. Specifically, we will assess plasma catecholamine levels during exercise and recovery, as well as oxygen consumption, substrate oxidation, and appetite over the 2-hour post-exercise period in young females with overweight or obesity. By elucidating the role of catecholaminergic stimulation as a potential regulator of fat mass loss, this research could provide valuable insights for optimizing exercise strategies in weight management and metabolic health.

CONDITIONS

Official Title

Acute Effects of Isoenergetic HIIE Vs. MICE on Key Parameters of Fat Mass Loss in Young Females with Overweight or Obesity

Who Can Participate

Age: 20Years - 45Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Women with overweight or obesity (BMI: 25-35 kg/m²)
Not Eligible

You will not qualify if you...

  • Use of contraceptives
  • Menopause
  • Irregular menstrual cycle
  • Medical contraindications to intense physical activity
  • Painful joints
  • Taking beta-blocker medication

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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2
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Trial Site Locations

Total: 1 location

1

Laboratório de Fisiologia e Metabolismo Aplicados à Educação Física

São Paulo, São Paulo, Brazil, 475

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

2

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