Actively Recruiting
Acute Efficacy and 6 Months Follow up After Electroconvulsive Therapy for Severe or Treatment Resistant Depression Predictors of Response, Side Effects, and Relapse
Led by Haukeland University Hospital · Updated on 2023-09-26
600
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
Sponsors
H
Haukeland University Hospital
Lead Sponsor
H
Helse Stavanger HF
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are studying the effects of electroconvulsive therapy (ECT) in patients with major depressive disorder, focusing on both immediate and long-term outcomes. This observational study evaluates patient and clinician ratings of depression symptoms, cognitive function, side effects, and relapse over a six-month period. The goal is to identify factors that predict response, remission, cognitive impairment, and relapse after ECT treatment. Participants receive ECT as part of their clinical care at Haukeland University Hospital or Stavanger University Hospital. The study tracks changes in depression and cognitive function from before treatment to after treatment and again at six months. Measurements include standardized depression scales and memory questionnaires to evaluate treatment effects and cognitive outcomes. During the study, patients complete assessments such as the Montgomery and Åsberg Depression Rating Scale, Beck Depression Inventory, Mini Mental State Examination, and Everyday Memory Questionnaire. Researchers also collect patient-rated and clinician-rated impressions of improvement and overall clinical status. The study includes monitoring of side effects and relapse, with follow-up visits lasting up to six months after treatment. Participation duration varies based on individual treatment schedules and follow-up.
CONDITIONS
Brief Title
Acute Efficacy and 6 Months Follow up After Electroconvulsive Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients treated with ECT for major depression (F31.3-5, F32, F33) at Haukeland University Hospital or Stavanger University Hospital after 2013
- Written consent to enrolment into the Regional Register for neurostimulation
You will not qualify if you...
- ECT performed on other indications than major depression
- No consent to the register
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 8 weeks
Participants receive electroconvulsive therapy for major depression and are assessed for changes in depressive symptoms and cognitive function during this period.
Multiple visits during treatment as part of routine care
Duration - 6 months
Participants are followed for 6 months after treatment to assess long-term efficacy, cognitive outcomes, and relapse.
Periodic visits during follow-up
Trial Site Locations
Total: 2 locations
1
Haukeland University Hospital
Bergen, Norway, 5021
Actively Recruiting
2
Stavanger University Hospital
Stavanger, Norway
Actively Recruiting
Research Team
U
Ute Kessler, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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