Study of Electroconvulsive Therapy Effects and 6-Month Follow-Up in Adults with Severe or Treatment-Resistant Depression

What this Trial Is About

Researchers are studying the effects of electroconvulsive therapy ECT in patients with major depressive disorder, focusing on both immediate and long-term outcomes. This observational study evaluates patient and clinician ratings of depression symptoms, cognitive function, side effects, and relapse over a six-month period. The goal is to identify factors that predict response, remission, cognitive impairment, and relapse after ECT treatment. Participants receive ECT as part of their clinical care at Haukeland University Hospital or Stavanger University Hospital. The study tracks changes in depression and cognitive function from before treatment to after treatment and again at six months. Measurements include standardized depression scales and memory questionnaires to evaluate treatment effects and cognitive outcomes. During the study, patients complete assessments such as the Montgomery and sberg Depression Rating Scale, Beck Depression Inventory, Mini Mental State Examination, and Everyday Memory Questionnaire. Researchers also collect patient-rated and clinician-rated impressions of improvement and overall clinical status. The study includes monitoring of side effects and relapse, with follow-up visits lasting up to six months after treatment. Participation duration varies based on individual treatment schedules and follow-up.

Acute Efficacy and 6 Months Follow up After Electroconvulsive Therapy