Study of Congestion Markers at Hospital Discharge in Adults with Acute Heart Failure and Preserved Ejection Fraction

What this Trial Is About

Researchers are studying patients with acute heart failure who have a preserved ejection fraction and are hospitalized due to worsening heart failure. The study aims to identify specific markers of congestionclinical signs, biological factors, and ultrasound findingsat the time of hospital discharge that are linked to the risk of death or rehospitalization within three months after leaving the hospital. Patients will undergo several evaluations before leaving the hospital, including a clinical exam focused on congestion, multiple types of Doppler ultrasounds cardiopulmonary, peritoneal, jugular, and renal, liver elastography, and blood sample collection for biological tests and biobanking. After discharge, participants will have telephone interviews and complete quality of life questionnaires at 3, 12, and 24 months. During the study, researchers will track rates of death from any cause, rehospitalization for acute heart failure, and intravenous diuretic treatments given in day hospitals or at home at 3, 12, and 24 months after discharge. They will also assess heart function symptoms, kidney function, natriuretic peptides, plasma volume, blood potassium levels, liver measurements, and quality of life. The study includes safety follow-up through telephone interviews and questionnaires over two years.

Acute Heart Failure With Preserved Ejection Fraction - COngestion Discharge Evaluation