Actively Recruiting

Phase Not Applicable
Age: 65Years - 85Years
All Genders
Healthy Volunteers
ID07522398

Acute Neuromuscular and Physiological Responses to Different Velocity Loss Thresholds During Power Training in Older Adults

Led by Hasselt University · Updated on 2026-04-13

42

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how different levels of fatigue during power training affect strength, movement, and muscle function in healthy older adults aged 65 to 85 years. The study aims to understand the immediate and recovery effects of varying fatigue levels on muscle soreness, exercise effort, and physical performance to help design safer and more effective training programs for this age group. Participants will complete three supervised power-training sessions on a pneumatic leg press machine about one week apart. Each session involves 4 sets with different fatigue levels: stopping when movement speed drops by 10% (low fatigue), stopping at 30% speed loss (moderate fatigue), or performing cluster sets with rest breaks to match the volume of the moderate fatigue session while maintaining low fatigue. Movement speed is continuously monitored during exercise. During the study, participants undergo strength and mobility tests before and after exercise, provide small blood samples to measure physiological responses, rate exercise effort, and report muscle soreness up to two days post-exercise. Researchers will measure outcomes like maximum voluntary contraction, torque development, muscle activity, muscle oxygenation, blood markers, functional performance tests, perceived exertion, and delayed muscle soreness over multiple timepoints. Participants are monitored for safety and recovery throughout the trial, which lasts about three weeks in total.

CONDITIONS

Brief Title

Acute Power Training Effects in Older Adults

Who Can Participate

Age: 65Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between 65 and 85 years old
  • Be able to live independently and perform everyday activities without help
  • Have not regularly done resistance or strength training in the past year
  • Be able to understand study instructions and communicate in the study language
  • Have a recent statement from your doctor confirming your heart and blood vessels are healthy enough for safe participation
Not Eligible

You will not qualify if you...

  • Have unstable heart disease, neurological disease, acute infection, or fever
  • Use non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen within 5 days before the study
  • Use whey protein, casein, or amino acid supplements within 1 month before the study
  • Have acute or chronic injuries to legs or lower body muscles
  • Have any injury or condition preventing safe leg extension exercises
  • Have had lower-limb joint replacement less than 6 months ago
  • Depend on walking aids
  • Currently participate in another interventional trial

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 3 weeks

Participants perform three supervised power-training sessions on a pneumatic leg press, each session separated by one week. Each session involves 4 sets of exercises with different fatigue levels monitored by movement speed. Researchers measure immediate and 24-hour post-session neuromuscular function, physiological responses, functional performance, perceived effort, and muscle soreness.

3 exercise sessions (in-person), approximately 1 week apart

Follow-up

Duration - Up to 2 days after each exercise session

Participants complete remote surveys rating muscle soreness at 24 and 48 hours after each exercise session to assess delayed onset muscle soreness.

Remote surveys after each session

Trial Site Locations

Total: 1 location

1

REVAL - Faculty of Rehabilitation Sciences

Diepenbeek, Flanders, Belgium, 3590

Actively Recruiting

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Research Team

M

Max Riesbeck, Master of Science

E

Evelien Van Roie, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

3

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