Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
NCT05085860

Acute Responses to Exercise in Females and Males With Symptomatic Atrial Fibrillation

Led by Ottawa Heart Institute Research Corporation · Updated on 2026-05-06

36

Participants Needed

1

Research Sites

268 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main purpose of this pilot project is to measure the feasibility of conducting a randomized crossover study examining short-term changes in atrial fibrillation (AF) symptoms in symptomatic females and males with paroxysmal or persistent AF when they engage in a standard week of exercise (i.e. moderate-intensity continuous training \[MICT\] or high-intensity interval training \[HIIT\]) compared to a control week (i.e. no moderate to vigorous exercise over 7 days).

CONDITIONS

Official Title

Acute Responses to Exercise in Females and Males With Symptomatic Atrial Fibrillation

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Paroxysmal or persistent atrial fibrillation
  • Resting ventricular rate less than 110 beats per minute (rate controlled)
  • Able to perform a symptom-limited exercise test
  • At least 40 years old
  • Self-reports having symptoms in the past 4 weeks
  • If female, self-reports being post-menopausal
  • Able to read and understand English or French
  • Agrees to sign informed consent
Not Eligible

You will not qualify if you...

  • Currently participating in routine exercise training
  • Unstable angina or uncontrolled diabetes mellitus
  • Diagnosis of severe mitral or aortic stenosis or hypertrophic obstructive cardiomyopathy with significant obstruction
  • Unable to access the Internet or a phone compatible with study requirements (iOS 10.0 or higher, Android 6.0 or higher)
  • Has an automated external defibrillator, implantable cardioverter defibrillator, or other pacemaker
  • Unwilling or unable to complete all three study conditions
  • Unable to provide written informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Ottawa Heart Institute

Ottawa, Ontario, Canada, K1Y4W7

Actively Recruiting

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Research Team

M

Matheus Mistura

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

3

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