Actively Recruiting
The Acute T-Rex (Timing of Resistance Exercise) Study
Led by University of Utah · Updated on 2025-04-03
20
Participants Needed
1
Research Sites
111 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary aim of this study is to evaluate if a single bout of AM vs PM resistance exercise has different effects on insulin sensitivity and sleep. A randomized cross-over trial be used to compare resistance exercise at two different times of the day. Each condition will take place in a laboratory setting. Each condition will consist of exercise, overnight sleep, and oral glucose tolerance tests the following day. The AM exercise will occur \~1.5 hours after habitual wake, and PM exercise will occur \~11 hours after habitual wake. After a 2-6 week washout, participants will complete the other condition. The hypothesis is that PM exercise will be more beneficial than AM exercise in improving insulin sensitivity. This study could identify if there is a better time of day to perform resistance exercise to decrease risk of developing Type 2 Diabetes Mellitus.
CONDITIONS
Official Title
The Acute T-Rex (Timing of Resistance Exercise) Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women, all ethnicities, aged 50-74 years
- Body mass index (BMI) between 25 and less than 45 kg/m²
- Stable weight with less than 5% change in the past 6 months
- Generally healthy individuals
- Not currently meeting recommended guidelines for aerobic or resistance exercise
You will not qualify if you...
- Uncontrolled cardiovascular, metabolic, kidney, or lung disease
- Cancer treatment within the past 5 years
- Untreated thyroid disease or other conditions affecting weight or energy metabolism
- Current use of weight loss or other medications impacting energy balance
- Bariatric surgery or extensive bowel removal in the past 2 years
- Current or recent (past 2 years) eating disorder
- Diagnosis of insomnia, sleep apnea, or other sleep and circadian disorders
- Non-English speaking
- Hemoglobin A1c (HbA1c) greater than 6.5%
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Utah HPER E Buildling
Salt Lake City, Utah, United States, 84112
Actively Recruiting
Research Team
T
Tanya M Halliday, PhD
CONTACT
S
Study Email Study Email
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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