Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07193914

Adaptation of the ECCCLORE Program for Patients With Addictive and Traumatic Problems: Feasibility and Acceptability

Led by Centre Hospitalier Universitaire de Nīmes · Updated on 2026-01-28

30

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying the feasibility and acceptability of a 12-week adaptation of the ECCCLORE program for patients facing both addiction and trauma-related problems, including complex posttraumatic stress disorder (cPTSD). This condition involves ongoing difficulties with emotion regulation, identity, and relationships after prolonged trauma exposure and is often linked to more severe addiction and behaviors like impulsivity and hostility. The study aims to address these intertwined issues to improve patient quality of life. The intervention being tested is the ECCCLORE program, a cognitive behavioral therapy originally developed for borderline personality disorder, now shortened to 12 weeks for this study. It involves weekly 2-hour group sessions with up to 10 participants, combined with 30-minute individual sessions after each group meeting. Sessions include discussions of the previous week, explanations of key concepts, and practices, plus support for home practice implementation. The program incorporates elements from Acceptance and Commitment Therapy and focuses on emotional regulation, distress tolerance, and interpersonal skills. Participants will be assessed at baseline and after 12 and 24 weeks for trauma, addiction, impulsivity, hostile attribution bias, aggressivity, flexibility, and depression through patient-reported measures. Primary outcomes focus on program feasibility, dropout rates, and acceptability of home practice by week 12. The study excludes certain psychiatric conditions and requires participants to be able to read and write French, with informed consent and health insurance coverage. Participation involves regular therapy sessions and follow-up assessments over the study period.

CONDITIONS

Brief Title

Adaptation of the ECCCLORE Program for Patients With Addictive and Traumatic Problems

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with one or more addictions
  • ASSIST questionnaire score ≥ 11 for alcohol and ≥ 4 for other substances
  • Diagnosis of PTSD and/or complex PTSD assessed by ITQ scale
  • Ability to understand, read, and write French
  • Given free and informed consent
  • Member or beneficiary of a health insurance plan
Not Eligible

You will not qualify if you...

  • Participating in another interventional drug or device study or Category 1 study within 3 months
  • Under safeguard of justice or state guardianship
  • Diagnosis of psychotic disorder
  • Severe cognitive impairment (MoCA score < 10)
  • Experiencing manic or hypomanic episode
  • Experiencing major depressive episode
  • Pregnant, parturient, or breastfeeding woman

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 12 weeks

Participants attend weekly group sessions and individual sessions as part of the ECCCLORE program designed to support patients with addiction and trauma issues.

Weekly visits (2-hour group session plus 30-minute individual session)

Trial Site Locations

Total: 1 location

1

CHU de Nîmes

Nîmes, Nîmes, France, 30029

Actively Recruiting

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Research Team

L

Laure Thebault

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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