Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
NCT05989451

Adaptation of Individual Dialectical Behavior Therapy Intervention for Transdiagnostic Treatment of Emotional Disorders

Led by Mackay Memorial Hospital · Updated on 2025-10-07

250

Participants Needed

1

Research Sites

160 weeks

Total Duration

On this page

Sponsors

M

Mackay Memorial Hospital

Lead Sponsor

N

National Science and Technology Council

Collaborating Sponsor

AI-Summary

What this Trial Is About

Anxiety and depressive disorders, referred to as emotional disorders, have high rates of prevalence, recurrence, and functional impairment. Transdiagnostic psychotherapy targeting shared features of these disorders has recently emerged. Dialectical behavior therapy (DBT) for the transdiagnostic treatment of emotional disorders is a promising approach, as results of preliminary studies for use in a broad range of mental disorders are encouraging. Since there is a lack of research on transdiagnostic psychotherapy in Taiwan, the investigators thus propose this 3-year randomized controlled trial to test the efficacy of a modified DBT for the treatment of transdiagnostic emotional disorders and to further evaluate whether the efficacy of modified DBT differs in the specific emotional disorders. The investigators expect that patients with emotional disorders receiving modified DBT are more likely to improve clinical outcomes, functioning, and quality of life.

CONDITIONS

Official Title

Adaptation of Individual Dialectical Behavior Therapy Intervention for Transdiagnostic Treatment of Emotional Disorders

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Mandarin Chinese-language proficiency sufficient to complete study questionnaire
  • Current diagnosis of depressive or anxiety disorder confirmed by SCAN interview
  • Age between 18 and 60 years
Not Eligible

You will not qualify if you...

  • Intellectual disability
  • Substance use disorder in the past three months
  • Bipolar disorder
  • Psychotic disorder
  • Organic brain disorder
  • Acute suicidality or history of frequent or recent suicide attempts
  • Recent (past six weeks) change in psychiatric medication or unwillingness to maintain stable dosage
  • Five or more sessions of cognitive behavioral therapy in past five years or unwilling to stop concurrent psychotherapy
  • Any mental or physical condition requiring hospital admission
  • Another medical condition likely to prevent participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

MacKay Memorial Hospital

Taipei, Taiwan

Actively Recruiting

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Research Team

H

Hui-Chun Huang, Ph.D

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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