Actively Recruiting

Phase Not Applicable
Age: 13Years - 40Years
All Genders
NCT05786898

Adaptation of the NEAR Cognitive Remediation Method to Child and Adult Autism by Including Social Scenarios and Skills

Led by Centre Hospitalier St Anne · Updated on 2023-03-28

66

Participants Needed

1

Research Sites

203 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The investigators currently provide the NEAR method (neuropsychological educational approach to cognitive remediation) for people with neurocognitive difficulties, without distinguishing between ASD and schizophrenia. However, the NEAR method does not address social cognition in the stimulated functions. The aim of this study is to add social scenarios to this neurocognitive method in order to improve not only neurocognitive functions, but also social cognition. Thus, NEAR would be in this adapted form a method that could be completely adapted to autism spectrum disorders in preadolescents and adults. The study will include participants aged 13-40 years, with a diagnosis of ASD. The NEAR TSA method will include 32 sessions: * one session (90-120 min, with one or two breaks) per week for 32 weeks (8 months), for minor participants. * two sessions (90 minutes each, with no breaks) per week for 16 weeks (4 months), for adult participants. The method includes 30 minutes of computerized exercises, 15 minutes of discussion on the exercises performed and the strategies applied, and the rest of the time for "bridging groups". Three evaluation are proposed: * an initial clinical and functional evaluation (T1), before the beginning of the program, * a second clinical, functional and neuropsychological evaluation (T2), within one month since the end of the program * a third clinical, functional and neuropsychologica evaluationl (T3), three months after the end of the program.

CONDITIONS

Official Title

Adaptation of the NEAR Cognitive Remediation Method to Child and Adult Autism by Including Social Scenarios and Skills

Who Can Participate

Age: 13Years - 40Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with Autism Spectrum Disorder (ASD) according to DSM5
  • Attending one of the outpatient units participating in the study
  • Diagnosis confirmed by ADI with at least one parent present or by ADOS
  • Score of at least 7 on the WISC5 (children) or WAIS4 (adults) comprehension subtest
  • Neuropsychological evaluation showing neurocognitive impairment
  • Ability to understand instructions for computer exercises
  • For children, attending a non-specialized school
  • Stability of psychotropic treatment for more than one month if applicable
Not Eligible

You will not qualify if you...

  • Known intellectual disability
  • Inability to understand questions or instructions during diagnostic interview
  • Proven neurological disease
  • Electroconvulsive therapy within the last 6 months
  • Uncorrected sensory perception disorder
  • Participation in another research study with an ongoing exclusion period
  • Treatment with daytime anxiolytics or anticholinergic correctors
  • Pregnant or breastfeeding women
  • Cognitive remediation in the last two years
  • Adults with heterogeneous developmental levels identified in diagnostic workup
  • Children not attending school

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

GHU Paris Saint-Anne

Paris, France

Actively Recruiting

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Research Team

L

Laura Nailler

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Adaptation of the NEAR Cognitive Remediation Method to Child and Adult Autism by Including Social Scenarios and Skills | DecenTrialz