Actively Recruiting

Phase Not Applicable
Age: 7Years - 17Years
All Genders
NCT05838235

Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome

Led by University Hospital, Toulouse · Updated on 2026-03-03

30

Participants Needed

1

Research Sites

283 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research study aims to evaluate the effect of a 6-month adapted physical activity program (APA) on the endurance capacities (evaluated as the maximum oxygen consumption \[VO2 peak\] on a cardiopulmonary exercise test) of children and adolescents with Marfan syndrome or related.

CONDITIONS

Official Title

Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome

Who Can Participate

Age: 7Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Genetically confirmed Marfan syndrome or related syndrome
  • Girl or boy aged 7 to 17
  • Informed and written consent signed by at least one of the two holders of parental authority
  • Patient affiliated to a social security scheme or equivalent
Not Eligible

You will not qualify if you...

  • Severe aortic dilation (aortic diameter > 45 mm)
  • Left ventricular failure (left ventricular ejection fraction <45%)
  • Severe mitral leakage grade 3 or higher
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU Toulouse

Toulouse, France

Actively Recruiting

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Research Team

T

Thomas EDOUARD, MD

CONTACT

F

Fernanda BAJANCA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

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