Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07498296

Adapting rHIRE and Sleep Monitoring in Parkinson's Disease

Led by University of Colorado, Denver · Updated on 2026-04-07

16

Participants Needed

1

Research Sites

36 weeks

Total Duration

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AI-Summary

What this Trial Is About

Exercise is a primary intervention for symptom management in Parkinson's Disease (PD). However, challenges related to transportation, mobility, and socioeconomic factors often hinder consistent participation in exercise programs. To promote increased access and participation, remote exercise programs offer a promising solution. The investigators previously showed that laboratory-based, high-intensity resistance exercise improves sleep efficiency in individuals with PD in a randomized, controlled, clinical trial. The investigators aim to adapt this protocol for remote delivery and to evaluate the usability of a remote sleep-monitoring device in people with Parkinson's Disease (PwP). Guided by the IDEAS framework for digital health intervention design, the investigators will modify the exercise protocol to ensure safety, accessibility, and fidelity in a home setting. Specific aims include: (1) assessing the adaptability of the HIRE protocol for remote implementation through participant acceptability ratings, adherence, exertion levels, and safety outcomes, (2) evaluating the usability of the Waveband sleep monitoring headband and adherence to night wear schedules, and 3) gather qualitative feedback through semi-structured interviews to understand participant perspectives on protocol design, session completion, and safety. By integrating behavioral theory, participant engagement, and real-world constraints, this research will inform scalable, home-based interventions that are both effective and responsive to the lived experiences of PwP. The findings will lay the groundwork for future clinical trials and broader dissemination of remote therapeutic strategies in neurodegenerative care.

CONDITIONS

Official Title

Adapting rHIRE and Sleep Monitoring in Parkinson's Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Currently residing in Colorado, USA
  • Diagnosed with Parkinson's Disease according to Movement Disorders Society criteria
  • Requires less than minimal assistance at home
  • Has internet access
  • Has a video-capable device
Not Eligible

You will not qualify if you...

  • Uncontrolled cardiovascular or pulmonary disease
  • Musculoskeletal injuries
  • Participating in Parkinson's Disease community exercise programs more than 3 days a week
  • Contraindicated for physical activity based on Physical Activity Readiness Questionnaire (PAR-Q)
  • Fall risk defined by taking more than 20 seconds on the 5 times sit to stand test or falling at least once per month in the past year
  • Virtual Montreal Cognitive Assessment (MoCA) score less than 18

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States, 80004-4159

Actively Recruiting

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Research Team

L

Lina Kleinschmidt, DPT

CONTACT

A

Aya Miften, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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