Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06827288

Adaptive Interventions for Emergency Department Patients With Opioid Use Disorder

Led by RAND · Updated on 2026-02-19

500

Participants Needed

1

Research Sites

182 weeks

Total Duration

On this page

Sponsors

R

RAND

Lead Sponsor

A

Arrowhead Regional Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

The ADAPT-ED study is a two-stage, sequential multiple assignment randomized trial (SMART) to inform the development of an adaptive intervention that is optimally effective in increasing long-term buprenorphine use for adults presenting to the ED with probable opioid use disorder (OUD).

CONDITIONS

Official Title

Adaptive Interventions for Emergency Department Patients With Opioid Use Disorder

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Presented for ED care at ARMC
  • Age 18 or older
  • Probable OUD diagnosis
  • Speak and understand English or Spanish
  • Have capacity to give informed consent
  • Provide a signed and dated informed consent form
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Arrowhead Regional Medical Center

Colton, California, United States, 92324

Actively Recruiting

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Research Team

M

Mariah Kalmin, PhD

CONTACT

P

P'trice Jones, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

6

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Adaptive Interventions for Emergency Department Patients With Opioid Use Disorder | DecenTrialz