Actively Recruiting
Adaptive Optics Retinal Imaging
Led by Food and Drug Administration (FDA) · Updated on 2026-05-08
150
Participants Needed
1
Research Sites
557 weeks
Total Duration
On this page
Sponsors
F
Food and Drug Administration (FDA)
Lead Sponsor
U
University of Maryland, Baltimore
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of the study is to collect and assess adaptive optics (AO) retinal images from human subjects in support of projects to demonstrate, advance, and enhance clinical use of AO technology.
CONDITIONS
Official Title
Adaptive Optics Retinal Imaging
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Are 21 years of age or older
- Can cooperate with instructions during adaptive optics imaging
- Can understand and sign informed consent
- Diagnosed with primary open angle glaucoma (for cohort 2)
You will not qualify if you...
- Are under 21 years of age
- Have conditions preventing adequate imaging (e.g., unstable fixation, media opacity)
- Have visual correction outside +4 to -8 diopters
- Have history of adverse reaction to mydriatic drops
- Have narrow iridocorneal angle or history of acute angle closure glaucoma
- Do not meet criteria for primary open angle glaucoma per American Academy of Ophthalmology (cohort 2)
- Have health conditions contraindicating oxygen supplementation (e.g., COPD, emphysema, asthma, obstructive or restrictive lung disease) (RBF experiment only)
- Depend on oxygen support or have baseline oxygen saturation below 95% (RBF experiment only)
- Tested positive for COVID-19 at enrollment or have acute/chronic photophobia
- Are working under direct supervision of Dr. Hammer
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Food and Drug Administration
Silver Spring, Maryland, United States, 20993
Actively Recruiting
Research Team
D
Daniel X Hammer, Ph.D.
CONTACT
Z
Zhuolin Liu, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
5
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