Actively Recruiting
Adaptive Optics Retinal Imaging in Inherited and Acquired Retinal Disorders
Led by The Hospital for Sick Children · Updated on 2026-04-28
200
Participants Needed
1
Research Sites
574 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a Prospective Observational study. The aim of the study is to understand the underlying photoreceptor, retinal pigment epithelium or retinal vascular aberrations in inherited and acquired retinal disorders. The study would use adaptive optics (AO) technology to assist in-vivo visualization of these retinal structures and ascertain changes from normal. Further, by using the AO imaging in patients before and after treatments, this study aims to better understand the effect of various interventions and develop AO as an outcome measure in various retinal disorders.
CONDITIONS
Official Title
Adaptive Optics Retinal Imaging in Inherited and Acquired Retinal Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Consent provided
- Aged 5 - 70 years
- Diagnosed with well documented retinal disorder
- Subjects aged 5 - 70 years with normal eye examination (Control group)
- Patients with strabismus and otherwise normal visual acuity and eye examination (Control group)
- Patients with unilateral eye diseases such as cataract, with a normal eye exam in the fellow eye (Control group)
You will not qualify if you...
- Inability to maintain a stable seated position
- Uncontrolled nystagmus, trembling, or movements of the eyes or head
- Presence of cataract or any opacity in the front of the eye that obscures retinal imaging
- Any general disease such as neurological disease affecting vision and retina
- History of previous uveitis, glaucoma, intra-ocular surgery, or photodynamic therapy
- High refractive errors (> +15D or < -15D) not correctable by the AO system
- History of photosensitivity or use of medicines causing photosensitivity
- Aphakia after cataract surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Hospital for Sick Children
Toronto, Ontario, Canada, M5G 1X8
Actively Recruiting
Research Team
A
Ajoy Vincent, MS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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